Although the brain plays a crucial role in the control of micturition, little is known about the structures involved. Identification of these areas is important, because their dysfunction is though to cause urge incontinence, a major problem in the elderly. In the cat, three areas in the brainstem and diencephalon are specifically implicated in the control of micturition: the dorsomedial pontin...

High frequency stimulation (HFS) of the subthalamic nucleus (STN) has been performed to reverse motor dysfunction in severe parkinsonian patients. Recent studies suggested that neural circuitry in the basal ganglia might regulate micturition function as well. In 15 adult male cats under ketamine anesthesia, in which spontaneous isovolumetric micturition reflex had been generated, we performed e...

These experiments were undertaken to examine whether both premotoneuronal mechanisms and direct actions on motoneurons could contribute to suppression of excitatory perineal reflex pathways during micturition. Intracellular recordings were obtained from motoneurons innervating the external urethral sphincter (EUS), external anal sphincter (EAS), and selected hindlimb muscles in decerebrate male...

Aims: To investigate whether intravesical lower pH induces a micturition threshold reflex change of anaesthetized rats. Methods: Thirteen female rats, anaesthetized by α-chloralose and paralyzed by pancurone bromide were used for the experiments. The micturition threshold volume was determined by repeated cystometry. Simultaneously bladder afferent activities in four and efferent activities in ...

conclusions we concluded that the occurrence of urination, as a response to cooling stimulation of the lower trunk, is correlated with infants’ age and amount of environmental temperature degree. results micturition occurred in response to decreased skin temperature of the lower trunk, during the first minute interval of napkin removal, in 287 of the infants (35.9%). totally, 428 infants (53.5%...

45 The functions of the lower urinary tract are controlled by complex pathways in 46 the brain that act like switching circuits to voluntarily or reflexly shift the activity of 47 various pelvic organs (bladder, urethra, urethral sphincter and pelvic floor muscles) from 48 urine storage to micturition. In this study, functional MRI (fMRI) was employed to 49 visualize the brain switching circuit...