Recurrent aphthous stomatitis consists on recurring oral ulcers of unknown etiology. Oral ulcers may be different in number and size depending on the clinical presentation, which also determines the time needed for healing. Moreover, there are factors associated to outbreaks but not implicated in its etiopathogenesis. When oral aphthosis has a known etiology, it is not considered as recurrent a...

n the article entitled “Two-year prevalence of minor aphtha in Tabriz, Northwest Iran” which was published in the winter issue of the third volume of the journal, a 0.3% prevalence rate for minor recurrent aphthous stomatitis (RAS) was reported. We attempted to continue studying the archives of Tabriz University of Medical Sciences Faculty of Dentistry until June 2008, to allow for a consecutiv...

Microbial factors may play a role in the pathogenesis of recurrent aphthous stomatitis (RAS). Because of similarities in the characteristics of peptic ulcers and oral aphthous ulcers, it seems reasonable to hypothesize that Helicobacter pylori (H. pylori) could play a role in the development of RAS. The aim of the present study was to determine the relationship between H. pylori and RAS using t...

J Dent Health Oral Disord Ther 2016, 5(5): 00170 Abbreviations: CREST: Calcinosis Raynaud Phenomenon Esophageal Dismotility Sclerodactyly Teleangiectasia; GERD: Gastro Esophageal Reflux Disease; CD: Celiac Disease; RAS: Recurrent Aphthous Stomatitis; MiRAS: Mikulicz’s Aphthae; MaRAS: Sutton’s Aphthae; HeRAS: Herpetiform Aphthae; PFAPA: Periodic Fever Aphthous Stomatitis Pharyngitis and Adenitis...

IL: interleukin RAS: recurrent aphthous stomatitis OBSERVATION Recurrent aphthous stomatitis (RAS) is a common cause of recurrent oral ulcers, which often leads to significant impairment of a patient’s quality of life. The underlying pathogenic mechanism remains unclear, and no treatment modality is uniformly effective. In this report, we describe the use of apremilast, an oral phosphodiesteras...

background: oral aphthous is one of the most common oral mucosal inflammatory disorders which are very painful. there is no definite medical strategy up to now for aphthous treatment. recently, some researchers have focused on immunomodulatory drugs such as tacrolimus and pimecrolimus in preventing aphthus recurrences. the aim of this study is to assess the effect of pimecrolimus cream against ...

Background and Aim. Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder characterized by recurrent, painful oral aphthae. Despite extensive research, the exact etiology of RAS remains elusive. Recently oxidant-antioxidant imbalance of the body has been implicated in the pathogenesis of recurrent aphthous stomatitis. Thus, the aim of the study was to evaluate the enzymatic anti...

microbial factors may play a role in the pathogenesis of recurrent aphthous stomatitis (ras). because of similarities in the characteristics of peptic ulcers and oral aphthous ulcers, it seems reasonable to hypothesize that helicobacter pylori ( h. pylori ) could play a role in the development of ras. the aim of the present study was to determine the relationship between h. pylori and ras using...

Recurrent aphthous stomatitis (canker sores) is a very common oral condition that remains incompletely understood. Presentation has been well-classified into minor, major or herpetiform subcategories based on clinical features, but exact etiology is unknown. Because etiology is unclear, treatments are primarily empiric and aimed at symptom reduction rather than prevention or cure. However, ther...