Objectives: Castleman’s disease (CD) is a group of rare atypical lymphoproliferative disorders classified as hyaline vascular (HV) and plasma cell (PC) types. CD may be closely mimicked by IgG4-related sclerosing disease (IgG4-SD) involving the lymph nodes. We retrospectively analyzed findings in patients with CD to elucidate the relationship between CD and IgG4-SD. Methods: Clinicopathological...

Abstract Introduction/Objective TAFRO syndrome (thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly) is a rare systemic inflammatory disorder. First reported in 2010, the majority of cases are from Japan, where it currently regarded as subtype HHV8-negative Multicentric Castleman Disease. Methods/Case Report We report case occurring 17-year old Puerto Rico. She originally pr...

Twenty years after its discovery [1], Kaposi’s sarcoma herpesvirus (KSHV) or human herpesvirus-8 (HHV-8) continues to be an enigmatic oncovirus, while AIDS-associated Kaposi’s sarcoma (AIDS-KS) remains a clinical challenge in endemic regions in Africa and for some patients receiving anti-retroviral therapy (ART) [2–4]. KSHV, a gamma-2 herpesvirus, is the etiological agent of Kaposi’s sarcoma (K...

Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...

In the present study, 360 male day-old broiler chicks were used to determine the effect of mixed livevaccines of Newcastle disease (ND) and infectious bronchitis (IB) on serum and local antibody responses toIB. Chicks were randomly divided into 12 treatment groups of 3 replicates and reared for 40 days on floorpens. Groups 1 to 5 received mixed ND and IB vaccine. Groups 7 to 11 received IB vacc...