Isolation of nonacosan-10-ol: The extract, after being digested with methanol and concentrated into a small volume, was chromatographed over silica gel with hexane to isolate a crystalline substance. The crystalline substance was recrystallized from hexane: mp 83 -84 ° , [a]D ± 0 ° , C29H60O (M® ion m/e 424; found: C 81.84%, H 14.30%; calc.: C 81,99%, H 14.24%). Acetylation of nonacosan-10-ol: ...

Phenacetin was first listed in the First Annual Report on Carcinogens (1980), as reasonably anticipated to be a human carcinogen, and analgesic mixtures containing phenacetin were first listed in the Fourth Annual Report on Carcinogens (1985), as known to be human carcinogens. The evidence for the carcinogenicity of these two substances is discussed separately; however, information on propertie...

We propose a Bayesian approach for estimating branching tree mixture models to compare drug-resistance pathways (i.e. patterns of sequential acquisition of resistance to individual antibiotics) that are observed among Mycobacterium tuberculosis isolates collected from treatment-naïve and treatment-experienced patients. Resistant pathogens collected from treatment-naïve patients are strains for ...

Mixture models capture heterogeneity in data by decomposing the population into latent subgroups, each of which is governed by its own subgroup-specific set of parameters. Despite the flexibility and widespread use of these models, most applications have focused solely on making inferences for whole or sub-populations, rather than individual cases. The current article presents a general framewo...

By means of a method previously described for demonstrating the growth-inhibitory and pneumococcidal power of normal serum-leucocyte mixtures, a study was made to determine the action of pneumococcus soluble substance on the growth of strains of pneumococci avirulent for rabbits and cats. It was found that the presence of a very small amount of the purified soluble substance of the homologous t...

Purpose. Creation of binder based on orthophosphoric acid and aluminum sulfate, study its structure physicochemical patterns formation, determination the properties structured mixtures for needs foundry. Methodology. In work, X-ray qualitative quantitative analysis was performed Rigaku Ultima IV unit, differential thermal STA 449 C Jupiter synchronous analyzer. Orthophosphoric acid, technical t...

The object of this work has been the isolation and identification of the fraction or fractions of pollen which were specifically active in clinical cases of hay fever. The fractions giving an immediate urticarial type of cutaneous reaction have been studied. No attempt was made to identify inactive material. The importance of a close relationship between chemical work and biological tests was e...

Schizophrenia is a complex psychiatric disorder with a characteristic disease course and heterogeneous etiology. While substance use disorders and a family history of psychosis have individually been identified as risk factors for schizophrenia, it is less well understood if and how these factors are related. To address this deficiency, we examined the relationship between substance use disorde...

Levamisole, an anthelmintic veterinary product is known to be used as an additive to cocaine that enhances the psychotropic effects of this substance. This mixture leads to reactions such as agranulocytosis, skin vasculitis and modulation of the immune system. Only the proper recognition, treatment of this entity and discontinuation of this substance consumption, leads to the disappearance of l...

Lactobacillus reuteri is a prominent member of the Lactobacillus population in the gastrointestinal ecosystem of humans, poultry, swine, and other animals. Reuterin is a newly discovered, broad-spectrum antimicrobial substance produced by this species during fermentation of glycerol. In this report, we describe procedures for (i) producing reuterin in sufficient amounts to isolate from a fermen...