Biodegradabilities of polymers and their composites in a controlled compost were described. Polycaprolactone (PCL) and poly(lactic acid) (PLA) were employed as biodegradable polymers. Biodegradabilities of PCL and PLA samples in a controlled compost were measured using a Microbial Oxidative Degradation Analyzer (MODA) according to ISO 14855-2. Sample preparation method for biodegradation test a...

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, the random switching of the modA gene controls expression of a phase-variable regulon of genes (a "phasevarion"), via differential methylation of the genome in the modA ON and OF...

We have studied the effect of a post-translational modification mutation upon four developmentally regulated glycosidases of Dictyostelium discoideum. The presence of the modA mutation affects the intracellular level of these multimeric enzymes differently. The level of alpha-glucosidase is unaffected in the modA mutant. The mutant cell contains only a very small fraction of the wild type beta-...

Non-typeable Haemophilus influenzae contains an N(6)-adenine DNA-methyltransferase (ModA) that is subject to phase-variable expression (random ON/OFF switching). Five modA alleles, modA2, modA4, modA5, modA9 and modA10, account for over two-thirds of clinical otitis media isolates surveyed. Here, we use single molecule, real-time (SMRT) methylome analysis to identify the DNA-recognition motifs ...

1.1. Recap. In the previous lecture we have considered the category CF := ⊕ n>0 FSn -mod. We have equipped it with two endofunctors, E = ⊕ n Res n n−1 and F = ⊕ n Ind n n+1 that are biadjoint. We have decomposed E into the direct sum of eigenfunctors, E = ⊕ i∈ZF Ei, for the endomorphism X that is given by XMm = Lnm for M ∈ FSn -mod, where Ln is the Jucys-Murphy element ∑n−1 i=1 (in). We have al...

1 Brown Representability First we introduce a portly abelian category A(S) for any preadditive category S. This will be a certain full subcategory of the category of all contravariant additive functors S −→ Ab. Modulo the fact that S is not assumed to be small, this is precisely what we call a right module over a ringoid in our Rings With Several Objects (RSO) notes. For background on portly ab...

Following the recommendation of the project technical reviewers, Mr. Rick Reed and Mr. Svein Hallsteinsen, to more explicitly take into account the established modelling languages in the telecom domain, this document consolidates information of relevance and establishes the relationship of Model Drive Architecture (MDA) and the Unified Modelling Language (UML) to the telecom languages. The lang...

The napEDABC genes of Bradyrhizobium japonicum encode the periplasmic nitrate reductase, an Mo-containing enzyme which catalyses the reduction of nitrate to nitrite when oxygen concentrations are limiting. In this bacterium, another set of genes, modABC, code for a high affinity ABC-type Mo transport system. A B. japonicum modA mutant has been obtained that is not capable of growing anaerobical...

Bacteriophage T4 encodes three ADP-ribosyltransferases, Alt, ModA, and ModB. These enzymes participate in the regulation of the T4 replication cycle by ADP-ribosylating a defined set of host proteins. In order to obtain a better understanding of the phage-host interactions and their consequences for regulating the T4 replication cycle, we studied cloning, overexpression, and characterization of...

In recent years, interest has been growing in the study of complex networks. Since Erdös and Rényi (1960) proposed their random graph model about 50 years ago, many researchers have investigated and shaped this field. Many indicators have been proposed to assess the global features of networks. Recently, an active research area has developed in studying local features named motifs as the buildi...