PURPOSE We assessed survival after radical prostatectomy, intensity modulated radiation therapy or conformal radiation therapy vs no local therapy for metastatic prostate cancer adjusting for patient comorbidity, androgen deprivation therapy and other factors. MATERIALS AND METHODS We identified men 66 years old or older with metastatic prostate cancer treated with radical prostatectomy, inte...

Nasopharyngeal carcinoma is an endemic disease within specific regions in the world. Radiotherapy is the main treatment. In recent decades, intensity-modulated radiation therapy has undergone a rapid evolution. Compared with two-dimensional radiotherapy and/or three-dimensional conformal radiotherapy, evidence has shown it may improve quality of life and prognosis for patients with nasopharynge...

Introduction: Radiotherapy is one of the effective methods in the treatment of cancer. In the recent methods of radiotherapy, intensity modulated radiotherapy (IMRT) technique by compensators is used. when photon beam passes the compensator, scattered photons can be generated within the compensator. The presence of scattered photons may complicate the design of compensators as...

The aim of this study was to evaluate the significance of performing patient specification quality assurance for patients diagnosed with glioblastoma multiforme treated with intensity modulated radiation therapy. The study evaluated ten intensity modulated radiation therapy treatment plans using 10 MV beams, a total dose of 60 Gy (2 Gy/fraction, five fractions a week for a total of six weeks tr...

The advanced developments in external beam radiation therapy (EBRT) over the past few decades have improved dose conformity to the target while minimizing dose to the surrounding organs at risk (OAR). Intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) are two commonly used EBRT techniques to treat cancer. In sliding window (SW) or dynamic IMRT, each radiati...

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Radiotherapy planning studies have confirmed dosimetric advantages of intensity-modulated radiation therapy over conventional and conformal radiation therapy. Utilization of intensity-modulated radiation therapy is ideal in head and neck cancer patients. Critical structures can be spared due to sharp dose gradients and limited organ motion with correct immobilization. Initial clinical results h...

The Agility multileaf collimator (Elekta AB, Stockholm, Sweden) has 160 leaves of projected width 0.5 cm at the isocenter, with maximum leaf speed 3.5 cms-1. These characteristics promise to facilitate fast and accurate delivery of radiotherapy, particularly volumetric-modulated arc therapy (VMAT). The aim of this study is therefore to create a beam model for the Pinnacle3 treatment planning sy...