نتایج جستجو برای: moisture adjustment factor maf

تعداد نتایج: 947572  

2015
Chuan Zhang Zhi‐Min Guo

Cellular muscular aponeurotic fibrosarcoma (c-Maf) is a member of the large macrophage-activating factor family. C-Maf plays important roles in the morphogenetic processes and cellular differentiation of the lens, kidneys, liver, T cells and nervous system, and it is particularly important in pancreatic islet and erythroblastic island formation. However, the exact role of c-Maf remains to be el...

Journal: :Science 2012
Hagen Wende Stefan G Lechner Cyril Cheret Steeve Bourane Maria E Kolanczyk Alexandre Pattyn Katja Reuter Francis L Munier Patrick Carroll Gary R Lewin Carmen Birchmeier

The sense of touch relies on detection of mechanical stimuli by specialized mechanosensory neurons. The scarcity of molecular data has made it difficult to analyze development of mechanoreceptors and to define the basis of their diversity and function. We show that the transcription factor c-Maf/c-MAF is crucial for mechanosensory function in mice and humans. The development and function of sev...

Journal: :American journal of clinical pathology 2009
Yasodha Natkunam Sara Tedoldi Jennifer C Paterson Shuchun Zhao Manuel Rodriguez-Justo Andrew H Beck Reiner Siebert David Y Mason Teresa Marafioti

c-Maf, a leucine zipper-containing transcription factor, is involved in the t(14;16)(q32;q23) translocation found in 5% of myelomas. A causal role for c-Maf in myeloma pathogenesis has been proposed, but data on c-Maf protein expression are lacking. We therefore studied the expression of c-Maf protein by immunohistochemical analysis in myelomas and in a wide variety of hematopoietic tissue. c-M...

2013
Tomoaki Eguchi Chiaki Kumagai Takashi Fujihara Thoru Takemasa Tetsuo Ozawa Osamu Numata

Aerobic exercise can promote "fast-to-slow transition" in skeletal muscles, i.e. an increase in oxidative fibers, mitochondria, and myoglobin and improvement in glucose and lipid metabolism. Here, we found that mice administered Mitochondria Activation Factor (MAF) combined with exercise training could run longer distances and for a longer time compared with the exercise only group; MAF is a hi...

2010
NORMAN CHIN PETER FRANCONERI

An annual mean heating value of 4,112 Btu/lb "as received" has been developed for municipal solid waste in the Spring Creek area of New York City. This is the lowest annual figure that I have seen published for a large metropolitan area in the United States. In view of the unusual value ob­ tained in this study, the authors should clearly explain why the heating value developed in this study is...

2013
Eunmee Hong Jasper Yik Derek F. Amanatullah Paul E. Di Cesare Dominik R. Haudenschild

OBJECTIVE ADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix. ADAMTS-12 is up-regulated during in vitro chondrogenesis and embryonic limb development; however, the regulation of ADAMTS-12 expression in cartilage remains unknown. The transcription factor c-Maf is ...

Journal: :Cancer research 1996
N Yamamoto V R Naraparaju S O Asbell

Serum vitamin D3-binding protein (Gc protein) can be converted by beta-galactosidase of B cells and sialidase of T cells to a potent macrophage activating factor, a protein with N-acetylgalactosamine as the remaining sugar moiety. Thus, Gc protein is the precursor of the macrophage activating factor (MAF). Treatment of Gc protein with immobilized beta-galactosidase and sialidase generates an ex...

Journal: :Blood 2011
Paul A Ney

The erythroblastic island was ultrastructurally identified as a common organizational unit of bone marrow more than 50 years ago.2 Erythroblastic islands are composed of erythroblasts, at various stages of maturation, and a central macrophage. The central macrophage supports erythroid cell survival and proliferation through intercellular signaling, and facilitates enucleation.3 Along this line,...

Journal: :Bioscience, biotechnology, and biochemistry 2012
Ayako Kikuchi Kogiku Shiba Tetsuo Ozawa Kentaro Nakano Kazuo Inaba Osamu Numata

Mitochondria activation factor (MAF) is a high-molecular-weight polyphenol purified from black tea that activates mitochondrial respiration. It increased the mitochondrial membrane potential and motility of sea urchin sperm, by up to 8%, to the same extent as sperm-activating peptides (SAPs) secreted by the egg. Unlike SAPs, MAF had no effect on sperm swimming behavior, suggesting that the mech...

Journal: :Molecular vision 2003
Daryle J DePianto Tom N Blankenship John F Hess Paul G FitzGerald

PURPOSE To examine the role of the c-Maf transcription factor in the regulation of non-crystallin lens fiber cell specific gene expression. METHODS Expression of lens fiber cell genes in c-Maf null mice was analyzed by immunohistochemical and RT-PCR methods. In addition, the effect of c-Maf on fiber cell gene promoter fragments was examined in co-transfection experiments. RESULTS Examinatio...

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