نتایج جستجو برای: monocarboxylic acid
تعداد نتایج: 747538 فیلتر نتایج به سال:
OLDENDORF, WILLIAM H. Carrier-mediated blood-brain barrier transport of short-chain monocarboxylic organic acids. Am. J. Physiol. 224(6) : 1450-l 453. 1973.-The permeability of the blood-brain barrier (BBB) to 15 14C-labeled organic acids of metabolic interest was studied by injecting the test acids rapidly into the common carotid artery and decapitating the rat 15 set later. Brain uptake durin...
I. Pig liver glycolic acid oxidase (glycolate: 02 oxidoreductase, EC 1.1.3.1 ) can function with either 2,6-dichlorophenolindophenol (DCIP) (Vmax----125o moles of glycolate per mole of ravin per rain) or 02 (Vmax = 620 moles of glycolate per mole of ravin per rain)9,1° as the electron acceptor. 2. Straight-chain monocarboxylic acids are non-competitive inhibitors of this enzyme with either glyc...
Neotrofin (AIT-082; leteprinim potassium) is transported out of brain by a saturable mechanism and in this study the mechanisms mediating this efflux were evaluated. Intracerebroventricular coadministration of [(14)C]Neotrofin with verapamil, a P-glycoprotein inhibitor, probenecid, an organic anion transporter inhibitor, 3-[[3-[2-(7-chloroquinolin-2-yl)vinyl]phenyl]-(2-dimethylcarbamoylethylsul...
During the growth of Penicillium stipitatum, stipitatonic acid was found to be the major component of the culture medium of young cultures, whereas stipitatic acid predominated in older cultures (3). This finding, and the easy chemical decarboxylation of stipitatonic acid to stipitatic acid in boiling water, suggested that the dicarboxylic acid was the precursor of the monocarboxylic acid. Furt...
During the growth of Penicillium stipitatum, stipitatonic acid was found to be the major component of the culture medium of young cultures, whereas stipitatic acid predominated in older cultures (3). This finding, and the easy chemical decarboxylation of stipitatonic acid to stipitatic acid in boiling water, suggested that the dicarboxylic acid was the precursor of the monocarboxylic acid. Furt...
A series of isoquercitrin (quercetin-3-O-β-d-glucopyranoside) esters with mono- or dicarboxylic acids was designed to modulate hydro- and lipophilicity and biological properties. Esterification of isoquercitrin was accomplished by direct chemoenzymatic reaction using Novozym 435 (lipase from Candida antarctica), which accepted C₅- to C12-dicarboxylic acids; the shorter ones, such as oxalic (C₂)...
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