BACKGROUND Findings of cerebral cortical atrophy, white matter lesions and microhemorrhages have been reported in high-altitude climbers. The aim of this study was to evaluate structural cerebral changes in a large cohort of climbers after an ascent to extreme altitudes and to correlate these findings with the severity of hypoxia and neurological signs during the climb. METHODS Magnetic reson...

Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological capacities. This practice may be unsafe in this remote alpine environment. However, robust data on medication during the ascent of Mont Blanc ...

Ungaran Mountain has a height of 2050 meters above sea level, this mountain is suitable for beginner climbers who want to know more about climbing hobbies, themselves only take 3-5 hours, depending on the speed walking, route also quite light and very heating before starting climb higher mountains. Thus many novice try conquer Mount Ungaran, armed with minimal experience climbing, risks they fa...

Introduction: Chronic mountain sickness (CMS) represents a syndrome of secondary polycythemia along with thrombocytopenia, altered hemorheology, pulmonary and systemic hypertension, and congestive heart failure, occurring due to hypobaric hypoxia-anoxia-induced erythropoiesis reported in both native mountain residents and new climbers after prolonged stays at high and extreme a...

STUDY OBJECTIVES Mechanical or inflammatory injury to pulmonary endothelial cells may cause impaired pulmonary gas exchange in acute mountain sickness (AMS) and noncardiogenic pulmonary edema in high-altitude pulmonary edema (HAPE). This study was designed to determine whether markers of endothelial cell activation or injury, plasma E- and P-selectin, were increased after ascent to high altitud...

The objectives of this research were to analyze terrain suitability Mount Talang Protected Forest for mountain tourism activities with the Geography Information System (GIS). Also estimate carrying capacity based on physical (PCC), real (RCC) and effective (ECC). Terrain is measured using 13 parameters, such as altitude, slope, land cover, rainfall, temperature, drainage, vegetation type, fauna...

Methods for measuring the ventilatory response to hypoxia (HVR) are reviewed. The criteria for success as a high altitude mountaineer are defined as freedom from acute mountain sickness (AMS) and ability to perform well at extreme altitude. The evidence for a brisk HVR being protective against AMS and associated with successful high altitude performance is reviewed. The contrary evidence of blu...