From November 1, 1982 through December 31, 1985, there were 19 centers and 382 patients that evaluated the effect of methylprednisolone sodium succinate (MPSS) on the septic syndrome. Seventeen of these centers enrolled 304 patients in a prospective, randomized, double-blind, placebo-controlled study to determine if early treatment with MPSS would decrease the incidence of severity of the adult...

Background:To investigate the mechanisms of myocardial ischemia induced changes of electrophysiological properties, influences of various ischemic-simulated Tyrode’s solutions on the changes of action potential characteristics were examined. Method:Action potential characteristics were measured during superfusion with various ischemic-simulated solutions (modified physiologic salt solution;MPSS...

SUMMARY We design and implement an integrated database system called 'multi-protein survey system' (MPSS), which provides a platform to retrieve information about many proteins at a time. This system integrates several important and widely used databases including SwissProt, TrEMBL, PDB and InterPro, plus useful references such as GO and KEGG to other databases. Users may submit a group of prot...

We have developed a public Web-based resource to facilitate access to global expression data for Arabidopsis, available at http://mpss.udel.edu/at. Developing an understanding of patterns and levels of transcriptional activity is the starting point for analyzing individual genes or gene families. Genome-wide transcriptional analyses are also revealing the relationship between the structure and ...

Recent studies in animal models indicate that recombinant human erythropoietin (rhEPO) is very effective in enhancing neurological recovery after spinal cord injury (SCI). We aimed to evaluate the effect of rhEPO plus methylprednisolone sodium succinate (MPSS) compared to MPSS alone to improve neurological function of patients after SCI in a randomized clinical trial. During a 15-month period 3...

This paper describes MPSS, a new proactive secret sharing protocol that provides mobility. Rather than requiring that the group of shareholders remain the same in every epoch, MPSS allows the membership of the group to change arbitrarily in each epoch. Mobility provides a needed methodology for a system administrator to use to determine group membership: identify a set of “fresh” nodes, and mov...

Inflammation plays a major pathological role in spinal cord injury (SCI). Although antiinflammatory treatment using the glucocorticoid methyprednisolone sodium succinate (MPSS) improved outcomes in several multicenter clinical trials, additional clinical experience suggests that MPSS is only modestly beneficial in SCI and poses a risk for serious complications. Recent work has shown that erythr...

For better guiding a system, senior managers should have accurate information. Using Data Envelopment analysis (DEA) help managers in this objective. Thus, many investigations have been made in order to find the most productive scale size (MPSS) for the evaluating decision making units (DMUs). In this paper we consider this case where there exist subsets of input and output variables to be inte...

MPSS (massively parallel signature sequencing) is a sequencing-based technology that uses a unique method to quantify gene expression level, generating millions of short sequence tags per library. We have created a series of databases for four species (Arabidopsis, rice, grape and Magnaporthe grisea, the rice blast fungus). Our MPSS databases measure the expression level of most genes under def...

Dentinal tubules occupy a substantial proportion of total dentin volume, especially of inner dentin. Resin-based sealer cements are known to penetrate deeply into dentinal tubules, but their ability to influence root strength is controversial. In this study, the contribution of dentinal tubules to shear strength and the influence of a resin-based sealer on shear strength were evaluated. Coronal...