نتایج جستجو برای: msu s

تعداد نتایج: 711769  

2015
Francesco Taus Marilina B. Santucci Emanuela Greco Matteo Morandi Ivana Palucci Sabrina Mariotti Noemi Poerio Roberto Nisini Giovanni Delogu Maurizio Fraziano Thomas Jens Scriba

A safer and more effective anti-Tuberculosis vaccine is still an urgent need. We probed the effects of monosodium urate crystals (MSU) on innate immunity to improve the Bacille Calmette-Guerin (BCG) vaccination. Results showed that in vitro MSU cause an enduring macrophage stimulation of the anti-mycobacterial response, measured as intracellular killing, ROS production and phagolysosome maturat...

2011
Tae-Jin Ju Jin-Myoung Dan Young-Je Cho So-Young Park

The present study elucidated the effect of the selective inducible nitric oxide synthase (iNOS) inhibitor N(6)-(1-iminoethyl)-L-lysine (L-NIL) on monosodium urate (MSU) crystal-induced inflammation and edema in mice feet. L-NIL (5 or 10 mg/kg/day) was administered intraperitoneally 4 h before injection of MSU (4 mg) into the soles of mice hindlimb feet. Twenty-four hours after MSU injection, fo...

The performance of MSU-S and its forms modified with phosphotungstic acid (HPW) and nickel (Ni) for the desulfurization and denitrogenation of model diesel fuel were studied. According to the results of the characteristic tests (N2 adsorption-desorption, XRD, SEM, and NH3-TPD), heteropoly acid incorporation causes higher acidity along with a negligible loss of structural a...

2015
Ashika Chhana Gerald Lee Nicola Dalbeth

BACKGROUND Gout is a chronic disease of monosodium urate (MSU) crystal deposition. Although hyperuricaemia is the central risk factor for development of gout, not all people with hyperuricaemia have subclinical MSU crystal deposition or indeed, symptomatic disease. The aim of this systematic literature review was to identify factors that contribute to MSU crystallization. METHODS A search was...

Journal: :Stroke 2015
Ritvij Bowry Stephanie Parker Suja S Rajan Jose-Miguel Yamal Tzu-Ching Wu Laura Richardson Elizabeth Noser David Persse Kamilah Jackson James C Grotta

BACKGROUND AND PURPOSE Faster treatment with intravenous tissue-type plasminogen activator (tPA) is likely to improve outcomes. Optimizing prehospital triage by mobile stroke units (MSUs) may speed treatment times. The Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit (BEST-MSU) study was launched in May 2014 using the first MSU in the United States to compare stroke management ...

Journal: :Journal of immunology 2017
Payel Sil Craig P Hayes Barbara J Reaves Patrick Breen Shannon Quinn Jeremy Sokolove Balázs Rada

Human neutrophils (polymorphonuclear leukocytes [PMNs]) generate inflammatory responses within the joints of gout patients upon encountering monosodium urate (MSU) crystals. Neutrophil extracellular traps (NETs) are found abundantly in the synovial fluid of gout patients. The detailed mechanism of MSU crystal-induced NET formation remains unknown. Our goal was to shed light on possible roles of...

Journal: :Journal of nanoscience and nanotechnology 2010
Hyung Ik Lee Jin Hoe Kim Ji Man Kim Seok Kim Jung-Nam Park Jae Sik Hwang Jei-Won Yeon Yongju Jung

Ordered nanoporous silica (MSU-H) with high surface area has been utilized as a solid substrate of a surface-modified hybrid sorbent for the application to the removal of U(VI). Carboxymethylated polyethyleneimine (CMPEI) with a strong complexing property has been introduced to the pore surface of MSU-H substrate. CMPEI-modified MSU-H (CMPEI/MSU-H) has been characterized by scanning electron mi...

2017
Hanif J. Khameneh Adrian W. S. Ho Federica Laudisi Heidi Derks Matheswaran Kandasamy Baalasubramanian Sivasankar Gim Gee Teng Alessandra Mortellaro

Gouty arthritis results from the generation of monosodium urate (MSU) crystals within joints. These MSU crystals elicit acute inflammation characterized by massive infiltration of neutrophils and monocytes that are mobilized by the pro-inflammatory cytokine IL-1β. MSU crystals also activate the complement system, which regulates the inflammatory response; however, it is unclear whether or how M...

2013
Valérie Gagné Louis Marois Jean-Michel Levesque Hugo Galarneau Mireille H Lahoud Irina Caminschi Paul H Naccache Philippe Tessier Maria JG Fernandes

INTRODUCTION Monosodium urate crystals (MSU), the etiological agent of gout, are one of the most potent proinflammatory stimuli for neutrophils. The modulation of MSU-induced neutrophil activation by inhibitory receptors remains poorly characterized. The expression of the myeloid inhibitory C-type lectin-like receptor (MICL) in neutrophils is downregulated by several proinflammatory stimuli, su...

2005
J. Alonso W. Barth A. Bechtold T. Beier K. Blaum G. Bollen P. Forck G. Gruber F. Herfurth C. Kozhuharov A. Krämer S. Minaev W. Quint D. Rodríguez A. Schempp S. Schwarz T. Valenzuela W. Vinzenz M. Vogel C. Weber G. Werth

J. Alonso , W. Barth , A. Bechtold , T. Beier , K. Blaum , M. Block , G. Bollen , L. Dahl , S. Djekic , P. Forck , G. Gruber , F. Herfurth , C. Kitegi , H.-J. Kluge , C. Kozhuharov , A. Krämer , S. Minaev , W. Quint , U. Ratzinger , H. Reich-Sprenger , D. Rodríguez , A. Schempp , S. Schwarz , S. Stahl , T. Valenzuela , J. Verdu , W. Vinzenz , M. Vogel , C. Weber , G. Werth 1 Univ. Mainz, GSI, U...

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