High-end graphics processing units (GPUs), such as NVIDIA Tesla/Fermi/Kepler series cards with thousands of cores per chip, are widely applied to high-performance computing fields in a decade. These desktop GPU cards should be installed in personal computers/servers with desktop CPUs, and the cost and power consumption of constructing a GPU cluster platform are very high. In recent years, NVIDI...

PURPOSE To assess the accuracy and precision of physiological parameters estimated by the modified Tofts and Kermode (mTK) model and the adiabatic approximation to the tissue homogeneity (AATH) model in dynamic contrast enhanced (DCE) MRI. METHODS Computer simulations were performed using the arterial input function (AIF) from Parker et al., and the multiple indicator, multiple path, indicato...

Insect immune defense is mainly based on humoral factors like antimicrobial peptides (AMPs) that kill the pathogens directly or on cellular processes involving phagocytosis and encapsulation by hemocytes. In Drosophila, the Toll pathway (activated by fungi and gram-positive bacteria) and the Imd pathway (activated by gram-negative bacteria) lead to the synthesis of AMPs. But AMP genes are also ...

Along with increased complexity of the models used for scientific activities and engineering, come diverse and greater uncertainties. Today, effectively quantifying the uncertainties contained in a model appears to be more important than ever. Scientific fellows know how serious it is to calibrate their model in a robust way, and decision-makers describe how critical it is to keep the best effo...

A novel nanocrystal system of montelukast (MTK) was designed to improve the transdermal delivery, while ensuring chemical stability labile compound. MTK Nanogel fabricated using nano dispersion method (Modified emulsification diffusion method). In pre-formulation study, there not any physicochemical interaction between drug and polymer had been evaluated by FTIR. The melting point found be 134-...

In this paper, we introduce new classes, MBk(α, λ, q, s, ρ) and MTk(α, λ, q, s, ρ) of meromorphic functions defined by using a meromorphic analougue of the Choi-Saigo-Srivastava operator for the generalized hypergeometric function and investigate a number of inclusion relationships of these classes. We also derive some interesting properties of these classes, which also includes radius problem ...

PURPOSE To characterize human gliomas using T1-weighted dynamic contrast-enhanced MRI (DCE-MRI), and directly compare three pharmacokinetic analysis techniques: a conventional established technique and two novel techniques that aim to reduce erroneous overestimation of the volume transfer constant between plasma and the extravascular extracellular space (EES) (Ktrans) in areas of high blood vol...

Transgenic expression of interleukin 10 (IL-10) in the islets of Langerhans leads to a pronounced pancreatic inflammation, without inflammation of the islets of Langerhans and without diabetes. A scattered infiltration of macrophages (Mtk) precedes localized accumulations of CD4 + and CD8 + T lymphocytes, B lymphocytes, and Mtk. This recruitment of inflammatory cells to the pancreas is somewhat...

Transgenic expression of interleukin 10 (IL-10) in the islets of Langerhans leads to a pronounced pancreatic inflammation, without inflammation of the islets of Langerhans and without diabetes. A scattered infiltration of macrophages (Mtk) precedes localized accumulations of CD4 + and CD8 + T lymphocytes, B lymphocytes, and Mtk. This recruitment of inflammatory cells to the pancreas is somewhat...

Genel hatlarıyla tahkim, irade serbestisi prensibine yer veren, devlet mahkemelerinde görülen yargılamaya kıyasen daha hızlı ilerleyen, gizlilik ilkesine hizmet eden, ihtilafın o alandaki uzman kişilerce nihayete erdirilmesini hedefleyen bir yargılama usulüdür. Tahkim yargılamasının yapılabilmesi için asli unsurlardan biri uyuşmazlığın tahkime elverişli olmasıdır. Tahkime elverişlilik, ilgili ü...