The low detection rate of multidrug-resistant tuberculosis (MDR-TB) is one the major obstacles to TB control in Thailand. Thus, this study aimed assess pre-diagnosis and pre-treatment attrition rates among patients suspected having MDR-TB, identify factors related attrition, determine turnaround times (TAT) diagnosis treatment pathway. A retrospective cohort analysis was conducted using a recor...

Background: Resistance of Mycobacterium Tuberculosis is a condition in which Anti-Tuberculosis (OAT) drugs are unable to kill the germs. One type resistance Multidrug Resistant Tuberculosis. (MDR-TB) TB caused by bacteria that resistant 2 types OAT, namely INH and Rifampin. The consequences if OAT deterioration health, increased costs, prolonged treatment, high rates therapy failure death.&#x0D...

embB306 mutants were detected in both ethambutol (EMB)-resistant and EMB-susceptible strains of Mycobacterium tuberculosis. Multidrug-resistant (MDR) strains had a higher proportion of embB306 mutants than non-MDR strains (odds ratio, 6.78; P < 0.001). The embB306 locus is a candidate marker for rapid detection of MDR and extremely drug resistant tuberculosis.

ABSTRACT Objective: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) the first two years of follow-up. Method: This is a prospective cohort study with 466 patients DECD who underwent transplantation 2015 and 2016 Brazil. A total 551 events were recorded. The largest incidence infectious occurred month after transplantation. Cytomeg...

&#x0D; Introduction : Multidrug-resistant TB (MDR TB) is a type of that resistant to at least two the first-line antimicrobials, isoniazid (INH) and rifampin (RMP), with or without resistance other antimicrobials. The factors causing MDR-TB were age, gender, education level, income, occupation, medication adherence, knowledge, attitudes, stigma, smoking habits, role PMO, side effects treatment....

Abstract.&#x0D; &#x0D; Multidrug resistance is still a major health problem worldwide. Biofilm formation was related to the of bacteria mechanism. Acinetobacter baumannii, one that cause nosocomial infections, given particular attention due its high prevalence resistance. The current study address observing antibacterial activity and antibiofilm Curcuma domestica rhizome extract against multidr...

Using multidrug-resistant (MDR)-transgenic mice, whose bone marrow cells express the human MDR1 gene at a level approximately equal to that found in many human cancers, we determined the efficacy of human-specific anti-P-glycoprotein monoclonal antibody MRK16 in overcoming multidrug resistance in an intact animal. MRK16 alone (2 mg) did not significantly affect the WBC counts of the MDR-transge...

Effective therapy of high-risk leukemia with established cytotoxic drugs may be limited by poor antitumor efficacy, systemic toxicity, and the induction of drug resistance. Here, we provide the first evidence that hydrolytically activated prodrugs may overcome these problems. For this purpose, VP16 was functionally blocked by hydrolytically cleavable carbonate linkers with unique characteristic...

Multidrug-resistant (MDR) Salmonella Concord has been associated with adoptees from Ethiopia. In 2009, Denmark saw an increase in MDR S. Concord infections among Ethiopian adoptees.