Escherichia coli strains that cause disease outside the intestine are known as extraintestinal pathogenic E. coli (ExPEC) and include pathogens of humans and animals. Previously, the genome of avian-pathogenic E. coli (APEC) O1:K1:H7 strain O1, from ST95, was sequenced and compared to those of several other E. coli strains, identifying 43 genomic islands. Here, the genomic islands of APEC O1 we...

Osteogenesis imperfecta (OI) or Brittle bone disease is the most common genetic cause of osteoporosis. The OI is caused by structural or quantitative defect in type I collagen. OI has the triad of fragile bone, blue sclerae and early deafness. O1 type V is characterized by recurrent multiple fractures in a child following ambulation with hyperplastic callus formation at the sites of fracture. T...

The isolates of Vibrio cholerae (Vc) non-O1 from the Sudanese outbreak in 1968 produce an enterotoxin similar to cholera toxin (CT) of Vc O1. However, we have observed that the subunit B of CT purified from a Sudanese isolate (strain $7) was a larger oligomer than that of Vc O1 (Yamamoto et al., 1983). This larger oligomer formation was suggested to be due to difference in the subunit B from CT...

Two systems are currently used to serologically type Vibrio cholerae O1 and non-O1 isolates. Antiserovar-serotype serum in the Smith system is produced in rabbits immunized with live whole-cell vaccines, and that in the Sakazaki system is produced in rabbits immunized with heat-killed vaccines. In neither system is the serovar-serotype-specific antigen clearly defined. During the course of a se...

Subjective Well‐Being and Income: Is There Any Evidence of Satiation? Many scholars have argued that once “basic needs” have been met, higher income is no longer associated with higher in subjective well-being. We assess the validity of this claim in comparisons of both rich and poor countries, and also of rich and poor people within a country. Analyzing multiple datasets, multiple definitions ...

We identified five different putative wav gene cluster types, which are responsible for the synthesis of the core oligosaccharide (OS) region of Vibrio cholerae lipopolysaccharide. Preliminary evidence that the genes encoded by this cluster are involved in core OS biosynthesis came from analysis of the recently released O1 El Tor V. cholerae genome sequence and sodium dodecyl sulfate-polyacryla...

A central step in the gating of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is the association of its two cytosolic nucleotide-binding domains (NBDs) into a head-to-tail dimer, with two nucleotides bound at the interface. Channel opening and closing, respectively, are coupled to formation and disruption of this tight NBD dimer. CFTR is an asymmetric adenosine...

Two constructs encoding the human micro-opioid receptor (hMOR) fused at its C terminus to either one of two Galpha subunits, Galpha(o1) (hMOR-Galpha(o1)) and Galpha(i2) (hMOR-Galpha(i2)), were expressed in Escherichia coli at levels suitable for pharmacological studies (0.4-0.5 pmol/mg). Receptors fused to Galpha(o1) or to Galpha(i2) maintained high-affinity binding of the antagonist diprenorph...

manual fingerprint classification algorithms are very time consuming, and usually not accurate. fast and accurate fingerprint classification is essential to each afis (automatic fingerprint identification system). this paper investigates a fingerprint classification algorithm that reduces the complexity and costs associated with the fingerprint identification procedure. a new structural algorit...

Abstract In this paper, income per capita convergence hypothesis is tested in selected OIC countries. For this purpose, we use the time series model and univariate KPSS stationary test with multiple structural breaks (Carrion-i-Silvestre et al. (2005)) over the period 1950-2008. The results show that most OIC countries could not catch up toward USA. Although because of some positive term of tra...