Extracellular multi-unit recording is a widely used technique to study spontaneous and evoked neuronal activity in awake behaving animals. These recordings are done using either single-wire or multiwire electrodes such as tetrodes. In this study we have tested the ability of single-wire electrodes to discriminate activity from multiple neurons under conditions of varying noise and neuronal cell...

Recent single-unit recording studies have clarified how multiple parameters of movement are signaled by individual cortical and cerebellar neurons, and also that multiple coordinate frames are utilized. Cognitive processes also modulate the firing of these neurons. The various signals and coordinate systems vary in time and evolve throughout a behavioral sequence, consistent with the demands of...

Multiple single-unit recording has become one of the most powerful in vivo electro-physiological techniques for studying neural circuits. The demand has been increasing for small and lightweight chronic recording devices that allow fine adjustments to be made over large numbers of electrodes across multiple brain regions. To achieve this, we developed precision motorized microdrive arrays that ...

The environment recording unit in coral skeletons: structural and chemical evidences of a biochemically driven stepping-growth process in coral fibres J. P. Cuif and Y. Dauphin Université Paris XI-Orsay, Bat. 504, Géologie ,UMR IDES, F-91405 Orsay, France Université Paris VI-UPMC, Micropaléontologie, t. 46–56 E5, 4 place Jussieu, UMR IDESF, F-75252 Paris cedex 05, France Received: 31 August 200...

8 There is a rather large gap between membrane properties of individual neurons and behavior or physiological events. To bridge this gap, we need to be able to understand the activity of individual neurons and how that activity contributes to neuronal circuits. Extracellular microelectrode recording, which focuses on neuronal action potentials of individual neurons as the “code” used by the int...

OBJECTIVE Drug resistant focal epilepsy can be treated by resecting the epileptic focus requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes. As commercial SEEG probes offer only a limited spatial resolution, probes of higher channel count and design freedom enabling the incorporation of macro and microelectrodes would help increasing spatial resolution and th...

The glycogen-depletion technique has become a well-established method for determining histologically the cross-sectional distribution of a single muscle unit. A major drawback of this method is its low yield of one depleted unit per experiment. Furthermore, this technique is particularly unsuited for determining the longitudinal distribution of single muscle units in long, broad muscles because...

Despite significant advances in robotics, commercially advanced prosthetics provide only a small fraction of the functionality of the amputated limb that they are meant to replace. Peripheral nerve interfacing could provide a rich controlling link between the body and these advanced prosthetics in order to increase their overall utility. Here, we report on the development of a fully integrated ...