A new immunoglobulin M (IgM) antibody capture enzyme immunoassay with peroxidase-labeled mumps antigen (dMACEIA) is described, and its suitability for practical diagnosis of acute mumps infection is evaluated. All 54 patients with proven mumps infection that were tested showed mumps-specific IgM antibodies. On the other hand, no specific IgM antibodies were present in 16 cases of suspected mump...

  Mass vaccination against viral infections such as mumps is a very noticeable and appropriate attempt in common health. Mumps infection has severe complications like deafness, infertility and meningitis. Attenuated live vaccine of mumps is produced and used to prevent the problems. Viral content in the monovalent vaccine is assayed with different methods. Nowadays international standards intro...

The association of mumps with peripheral facial paralysis has been suggested, but its pathogenesis remains unclear. An 8-year-old girl simultaneously developed left peripheral facial paralysis, ipsilateral cervical herpes zoster, and bilateral mumps sialadenitis. Elevated anti-mumps and anti-varicella zoster virus IgM antibodies in serological testing indicated recent infection of mumps and rea...

IKEDA, S., CHIBA, S., CHIBA, Y., NAKAO, T. and Fuuui, S. Epidemiological, Clinical and Serological Studies on Epidemic of Mumps in an Infant Nursery. Tohoku J. exp. Med., 1971, 105 (4), 327-337 •\ Epidemiological, clinical and serological studies on the epidemic mumps were carried out in 47 infants in Central Babies Home, Sapporo. Furthermore by utilizing fluorescent antibody tests the influenc...

The mumps virus is a negative-strand RNA virus in the family Paramyxoviridae. Mumps infection results in an acute illness with symptoms including fever, headache, and myalgia, followed by swelling of the salivary glands. Complications of mumps can include meningitis, deafness, pancreatitis, orchitis, and first-trimester abortion. Laboratory confirmation of mumps infection can be made by the det...

Mumps is a highly contagious viral infection that became rare in most industrialized countries following the introduction of measles-mumps-rubella (MMR) vaccine in 1967. The disease, however, has been re-emerging with several outbreaks over the past decade. Many clinicians have never seen a case of mumps. To assist frontline healthcare providers with detecting potential cases and initiating cri...

BACKGROUND Mumps emerged among highly vaccinated populations in the Netherlands. This offered a unique opportunity to study mumps virus transmission. In particular the extent to which asymptomatic infections in vaccinated people contribute to ongoing mumps virus transmission is uncertain. Insight into this could help project the future burden of mumps in vaccinated populations. We therefore stu...

Prior to the adoption of widespread vaccination programs, mumps virus was the leading cause of virus-induced central nervous system (CNS) disease. Mumps virus-associated CNS complications in vaccinees continue to be reported; outside the United States, some of these complications have been attributed to vaccination with insufficiently attenuated neurovirulent vaccine strains. The development of...

Introduction of MMR vaccine was believed to have resulted in a decline in the incidence of measles, mumps and rubella infections. However, recent reports suggest the re-emergence of mumps infection worldwide in the vaccinated populations. It was proposed that the reason for this re-emergence was poor efficacy of MMR vaccine. The present study was aimed to investigate mumps infection in MMR vacc...

Because of its various manifestations mumps is now considered to be a generalized infection characterized principally by involvement of the parotid and submaxillary glands. Among the complications of mumps-virus infection are meningoencephalitis, gastro-enteritis, orchitis, mastitis, pancreatitis, and subacute thyroiditis. Sometimes one of these disorders constitutes the only manifestation of i...