in order to evaluate the effect of berberis vulgaris extract on the experimental ulcers of cutaneous leishmaniasis (cl) on balb/c mice, a study was undertaken over a 12 months period. forty balb/c mice were divided into 2 main groups a and b. each main group in turn was divided into 5 sub groups of 4 mice and each sub group were inoculated subcutaneously by 0.1ml liquid phase culture containing...

background: since embryonic stem (es) cells have the dual ability to proliferate indefinitely and differentiate into multiple tissue types, es cells could potentially provide an unlimited cell supply for human transplantation. objective: in order to study the differentiation of mouse embryonic stem (mes) cells, they were cultured in suspension by using es media without leukemia inhibitory facto...

The mammalian skin can support hair follicle formation during embryonic development, but this ability is lost as the matures. We have previously shown that, in murine starting at day 16.5 (E16.5), dermal fibroblasts contained two distinct lineages with different functions. upper papillary population supports of new follicles. However, mechanism by which are established remained undefined. By pe...

Alternatively activated (also known as M2) macrophages are involved in the repair of various types of organs. However, the contribution of M2 macrophages to cardiac repair after myocardial infarction (MI) remains to be fully characterized. Here, we identified CD206+F4/80+CD11b+ M2-like macrophages in the murine heart and demonstrated that this cell population predominantly increases in the infa...

The toxicity of interferon to bone marrow was studied by the use of in vitro colony forming assays for hemopoietic cells. In the same study the relative inhibitory effects of two clinically common interferon preparations, leukocyte and fibroblast interferons, were compared with regard to their effect on both myeloid [colony-forming unit, culture (CFUc)] and erythroid [colony-forming unit, eryth...

INTRODUCTION Rheumatoid arthritis is an autoimmune arthritis characterized by joint destruction. Anti-citrullinated protein antibodies are pathologic in rheumatoid arthritis, but the role of the citrullinated proteins themselves is much less clear. Citrullination is the conversion of the arginine residues of a protein to citrulline. In the inflamed rheumatoid joint there is increased protein ci...

The corrosion resistance and biocompatibility of a novel Fe50Cr18Mo10C20Si2 metallic glass (Fe–MG), are studied by electrochemical measurements indirect contacting cytotoxicity assays for biomedical applications. In Hank’s solution, the Fe–MG shows better than SS316L, evidenced larger polarization in potentiodynamic impedance spectroscopy (EIS) tests, lower amounts released ions during immersio...

The in vitro culture conditions allowing survival and initial proliferation of murine primordial germ cells from 10.5 days post coitum embryos, which include the use of a murine embryonal fibroblast (STO) feeder, were applied to 21 human seminomas, composed of tumour cells which are considered as the malignant counterparts of human primordial germ cells. Cells from 18 seminomas attached poorly ...