نتایج جستجو برای: myeloproliferative neoplasms
تعداد نتایج: 500280 فیلتر نتایج به سال:
Philadelphia-chromosome negative chronic myeloproliferative neoplasms are clonal hematologic diseases characterized by hematopoietic progenitor independence from or hypersensitivity to cytokines. The cellular and molecular mechanisms involved in the pathophysiology of myeloproliferative neoplasms have not yet been fully clarified. Pathophysiologic findings relevant for myeloproliferative neopla...
We analyzed 636 patients with diverse myeloproliferative neoplasms or myelodysplastic/myeloproliferative neoplasms for mutations of the Casitas B-cell lymphoma gene (CBL(mut)) in exons 8 and 9 and performed correlations to other genetic alterations. CBL(mut) were detected in 63 of 636 (9.9%) of these selected patients. CBL(mut) were more frequent in myelodysplastic/myeloproliferative neoplasms ...
Structure of RAS-GTP: image accompanying the review article on 'RAS diseases in children' in this issue. 1650 Somatic mutations of calreticulin in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms Luca Malcovati, et al.
Mastocytosis is one of eight subcategories neoplasms. Classification Myeloproliferative Tumors Lymphoid Tissues and hematopoietics 2008 the World Health Organization; a heterogeneous group myeloproliferative diseases that distinguished by excessive proliferation mast cells morphologically immunophenotypically atypical, in addition to accumulation these or more organs tissues, including skin, bo...
| 1634 | haematologica | 2009; 94(12) The World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues includes within myeloid neoplasms the category “Myelodysplastic/myeloproliferative neoplasms”. According to Vardiman et al., these are “clonal myeloid neoplasms that at the time of initial presentation have some clinical, laboratory or morphologic findings tha...
Myeloproliferative neoplasms are clonal diseases of hematopoietic stem cells characterized by myeloid hyperplasia and increased risk of developing acute myeloid leukemia. Myeloproliferative neoplasms are caused, as any other malignancy, by genetic defects that culminate in the neoplastic phenotype. In the past six years, since the identification of JAK2V617F, we have experienced a substantial i...
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