introduction: nicotinamide adenine dinucleotide phosphate (nadph) oxidase-2 (nox2) is one of the predominant sources of ros production during myocardial ischemia-reperfusion and can be induced by angiotensin ii. the evidence suggests that pharmacological blockers of renin-angiotensin system can exert direct tissue effects independent of their ability to regulate blood pressure. the mechanism(s)...

objective(s): electrical inhomogeneity between ischemic and non ischemic myocardium is the basis of arrhythmia which occurs following coronary artery occlusion. the leakage of potassium from the ischemic region to the non ischemic region is very effective in the generation of these arrhythmias. the aim of this study is to research the effect of atp-dependent potassium (katp) channel blocker (gl...

Myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. The outcome of myocardial necrosis varies depending on the extent of the damage (Donald 2001, Jubb 1993, Radostits 1994, Vanvaleet 1986). Myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (Gonder 1...

objective: the risk of cardiac death in diabetic patients is 3 times more than non-diabetics. but it is not determined who need cardiac screening. about 41% of diabetic patients with silent ischemia are missed. the carotid intima-media thickness (cimt) and ankel brachial index are two independent,simple and non invasive method in vascular complications diagnosis in diabetic patients.the aim of ...

background: an electrocardiogram (ecg) can provide information on subclinical myocardial damage. the presence, and more importantly, the quantity of coronary artery calcification (cac), relates well with the overall severity of the atherosclerotic process. a strong relation has been demonstrated between coronary calcium burden and the incidence of myocardial infarction, a relation independent o...

background: it has been reported that the chronic oral administration of garlic homogenate protected the rat heart from in vitro ischemic reperfusion injury. however, the biological effects of garlic juice on the heart are expected to be different from oral administration of it. objective: the present study was designed to investigate the effect of garlic juice on the isolated rat heart in isch...

objective(s) dracocephalum moldavica (d. moldavica) have been traditionally used as a cardiotonic agent in the folk medicine of some regions of iran. in the present study, effects of total extract of d. moldavica on ischemia/reperfusion induced arrhythmias and infarct size investigated in isolated rat heart. materials and methods the isolated hearts were mounted on a langendorff apparatus then ...

myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. the outcome of myocardial necrosis varies depending on the extent of the damage (donald 2001, jubb 1993, radostits 1994, vanvaleet 1986). myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (gonder 1...