In the title compound, [Ni(C(26)H(20)N(4)O(2))]·0.5C(4)H(10)O, the central metal ion is coordinated by four atoms of the tetra-dentate picolinamide ligand, forming a slightly distorted square-planar configuration, with an average Ni-N(pyridine) distance of 1.94 Å and an average Ni-N(amide) distance of 1.83 Å. The asymmetric unit contains one half-molecule of diethyl ether; this solvent molecule...

The crystal structure of the title compound, C6H6N2O2·H2O, consists of N-hy-droxy-picolinamide and water mol-ecules connected through O-H⋯O and N-H⋯N hydrogen bonds. The O-H⋯O inter-actions and π-π stacking inter-actions between the pyridine rings [centroid-centroid distance = 3.427 (1) Å] organize the components into columns extending along the b axis and the N-H⋯N hydrogen bonds link these co...

In the title compound, C(10)H(4)Cl(4)N(4)O, the pyridine and pyrimidine rings are nearly perpendicular to each other, the dihedral angle between them being 86.60 (10)°. In the crystal structure, the N and O atoms in the amide group are involved in inter-molecular hydrogen bonds, forming a one-dimensional chain along the c axis.

The pathway of oxidation of picolinamide (pyridine-2-carboxamide) by a Gram-negative rod has been elucidated. Under conditions of high pH, restricted aeration and high substrate concentration, whole cells released 2,5-dihydroxypyridine into culture supernatants. Sodium arsenite at 5mm caused whole cells to accumulate 6-hydroxypicolinate, and, at 1mm, pyruvate, in culture media. Whole cells oxid...

In the title compound, C(12)H(7)Cl(2)FN(2)O, the dihedral angle between the phenyl and pyridine rings is 42.5 (2) Å and an intramolecular N-H⋯N hydrogen bond occurs. The crystal structure is stabilized by C-H⋯O, C-H⋯F and C-Cl short contacts.