Background and Aims: Formaldehyde, a colorless aldehyde with pungent odor, has negative effects on systems of the body. Considering, there are a little data about protective substances against kidney damage induced by formaldehyde, the aim of the present study was to examine the effects of different doses of N-acetyl cysteine on biochemical and histopathological parameters in k...

there are a limited number of food and drug administration ( fda)-approved medications for the treatment of autism. meanwhile, oxidative stress and neuroinflammation are supposed to play a causative role in autism. n-acetylcysteine may provide cystine, a precursor for glutathione (gsh), which is an important antioxidant factor in the brain. we here report a child with autism, whose symptoms wer...

The purpose of this study was to evaluate the effects of different time combinations of dexamethasoneand acetylcysteine on experimentally induced corneal ulcers in dogs. Experimental corneal wounds werecreated surgically to the anterior one third of the cornea in the center of all eyes of 15 mixed breed dogs. The eyes were divided into five groups according to planned post-operative medications...

BACKGROUND: Few studies compared the efficacy of theophylline with N-acetylcysteine or evaluated the efficacy of combination therapy in the prevention of contrast-induced nephropathy (CIN). We compared the efficacy of theophylline, N-acetylcysteine, and the combination of these agents in the prevention of CIN. METHODS: This randomized controlled trial was conducted on 96 patients referring cons...

BACKGROUND Few studies compared the efficacy of theophylline with N-acetylcysteine or evaluated the efficacy of combination therapy in the prevention of contrast-induced nephropathy (CIN). We compared the efficacy of theophylline, N-acetylcysteine, and the combination of these agents in the prevention of CIN. METHODS This randomized controlled trial was conducted on 96 patients referring cons...

N-acetylcysteine (NAC) is a drug  used  widely and effectively in oral  and  ‎intravenous  forms  as  a  specific  antidote  for acetaminophen poisoning.  In children ‎considering the toxic dose of acetaminophen ingested by the patient and the body weight, the ‎physician prescribes a specific dose of NAC. There is always a risk of  iatrogenic overdose of  ‎NAC  which can cause different mild to...

N-acetylcysteine (NAC) is a drug  used  widely and effectively in oral  and  ‎intravenous  forms  as  a  specific  antidote  for acetaminophen poisoning.  In children ‎considering the toxic dose of acetaminophen ingested by the patient and the body weight, the ‎physician prescribes a specific dose of NAC. There is always a risk of  iatrogenic overdose of  ‎NAC  which can cause different mild to...

N-acetylcysteine is assumed to reverse nitrate tolerance by replenishing depleted intracellular sulfhydryl groups, but data on interactions of N-acetylcysteine and nitrates in patients with stable angina are controversial and disappointing. Therefore, we studied the effect of N-acetylcysteine on nitrate responsiveness of epicardial arteries and of the venous system (assessed as changes in effec...

BACKGROUND Contrast-induced nephropathy (CIN) remains a leading cause of acute renal failure in hospitalized patients. N-Acetylcysteine has been studied previously for the prevention of CIN, resulting in mixed findings. OBJECTIVE The objective of this study was to determine the impact of N-acetylcysteine on the development of CIN in order to guide its use at community, teaching hospitals. M...