Bacterial pathogens have specific virulence factors (e.g., toxins) that contribute significantly to the virulence and infectivity of microorganisms within the human hosts. Virulence factors are molecules expressed by pathogens that enable colonization, immunoevasion, and immunosuppression, obtaining nutrients from the host or gaining entry into host cells. They can cause pathogenesis by inhibit...

Neurovascular compression syndromes (NVC) result from a compression of the entry/exit zone of cranial nerves by a vessel at the surface of the brainstem. Surgical intervention planning (SIP) for NVC enables a comprehensive spatial understanding of the patient specific anatomy. Specifically, brainstem, vessels and nerves are segmented in NVC SIP. To support segmentation for NVC SIP, we propose a...

BACKGROUND Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenetic role. Recently, we graded scleroderma microangiopathy by nailfold videocapillaroscopy (NVC) into three NVC patterns (early, active and late). The aim of the present study was to confirm, in a larger number of SSc patients, the presence of three patterns of microvascular...

Abstract High production rates and wide areas of application water-soluble polymers indicate their potential occurrence in wastewater. Poly(N-vinylcaprolactam) (PNVCL) is such a poorly biodegradable polymer with non-ionic, non-sticky, non-toxic thermosensitive properties. Its field applications covers being constituent aerosol sprays, pump lotions as well its usage flocculant wastewater treatme...

Recent data suggest a causal relationship between essential hypertension and neurovascular compression (NVC) at the rostral ventrolateral medulla. An increase of central sympathetic outflow might be an underlying pathomechanism. The sympathetic nerve activity to muscle was recorded in 21 patients with hypertension with NVC (NVC+ group) and in 12 patients with hypertension without NVC (NVC- grou...

OBJECTIVES Dermatophytes, belonging to genera including Trichophyton, Epidermophyton, and Microsporum, are the causative agents of superficial fungal infections, prevalences of which are estimated to be as high as 25% in the worldwide population. This study evaluated the activity of topical formulations of NVC-422 (sodium 2-[dichloroamino]-2-methylpropane-1-sulfonate), the lead compound in a ne...

This study looks at how people rate specific non-verbal cues (NVC) with regard to the presence and persuasiveness of the speaker. The first study (N = 1500) was conducted to attempt to isolate specific non-verbal signals (hands and feet) that were related to ratings on influence and persuasiveness. In the second study, over 600 people rated a high quality video of an actor speaking. A sex by ag...

BACKGROUND Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and visceral organs. The microangiopathy is early detectable in the course of the disease by nailfold videocapillaroscopy (NVC), a non-invasive technique with a high diagnostic value. OBJECTIVE Aim of our study was to evaluate the feasibility of a quantitative score and its correlation with the ...