Onychomadesis is a reversible, painless, noninflammatory condition in which there is proximal shedding of the nail plate from the nail matrix. It can occur in fingernails, toenails or both. It may be secondary to systemic disorders, high fevers, bullous dermatoses, Kawasaki disease, infections (streptococcal infections and measles), zinc deficiency, local trauma, acute paronychia, and drug reac...

background: nail disorders comprise approximately 10% of all dermatological conditions. abnormalities in the color of nails are called ungal dyschromia or chromonychia. ungual dyschromia may be endogenous or exogenous. yellow discoloration of the nails has been reported during the last years as separate observation related to drug administration, during hemodialysis and associated with pulmonar...

Editorials Onychomadesis and hand, foot and mouth disease – is there a connection? Citation style for this article: Haneke E. Onychomadesis and hand, foot and mouth disease – is there a connection?. Onychomadesis is the spontaneous separation of the nail plate from the matrix, a kind of proximal onycholy-sis, and is a common phenomenon due to arrest of nail formation for a certain period. Short...

Background: The nails of hands and feet are involved in the course of many dermatoses and some systemic diseases. They may have diagnostic or prognostic value in some diseases. Objective: The aim of this study was to evaluate nail lesions in patients referred to Dermatology Department of Sina Hospital in Hamadan from April 1999 to April 2000. Patients and Methods: This cross-sectional des...

an 8-year old boy with polyarthritis and nail involvement is presented in this report. nail involvement in reiter's syndrome is a rare condition that may include painless erythematous nduration of the base of the nail fold; subungual parakeratotic scaling and thickening opacification, ridging of the nail plate.

Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by onychomadesis (nail shedding), occurred during summer and fall 2008 in Valencia, Spain. Fecal samples from onychomadesis patients, who did or did not have previous HFMD, and from healthy children exposed to onychomadesis patients tested p...

Introduction: Onychomadesis refers to the proximal separation of nail plate from matrix following a temporary arrest in formation, leading shedding. While it can be consequence multiple aetiologies, is uncommon childhood. To our knowledge, this first case reporting association between onychomadesis and hand-foot-and-mouth disease context primary health care Portugal. Case description: A previou...

Nail biopsy is a safe and useful technique for diagnosis and management of many nail conditions. A basic understanding of nail anatomy and biology is a prerequisite for a successful nail biopsy. The patient must be adequately prepared and there needs to be excellent anesthesia and hemostasis. The type of nail biopsy depends largely on the location of the pathology in the nail unit. The techniqu...

We hypothesised that Hansen Solubility Parameters (HSPs) can be used to predict drug-nail affinities. Our aims were to: (i) determine the HSPs (δD, δP, δH) of the nail plate, the hoof membrane (a model for the nail plate), and of the drugs terbinafine HCl, amorolfine HCl, ciclopirox olamine and efinaconazole, by measuring their swelling/solubility in organic liquids, (ii) predict nail-drug inte...