نتایج جستجو برای: nanoencapsulation

تعداد نتایج: 268  

Journal: :Biomacromolecules 2010
Zheng-liang Zhi Bo Liu Peter M Jones John C Pickup

This paper describes the use of a layer-by-layer nanocoating technique for the encapsulation of insulin-producing pancreatic beta-cell spheroids (pseudoislets) within chitosan/alginate multilayers. We used pseudoislets self-organized from a population of the insulinoma cell line MIN6, derived from a transgenic mouse expressing the large T-antigen of SV40 in pancreatic beta-cells, as an experime...

2014
Renata V Contri Luiza A Frank Moacir Kaiser Adriana R Pohlmann Silvia S Guterres

Capsaicin, a topical analgesic used in the treatment of chronic pain, has irritant properties that frequently interrupt its use. In this work, the effect of nanoencapsulation of the main capsaicinoids (capsaicin and dihydrocapsaicin) on skin irritation was tested in humans. Skin tolerance of a novel vehicle composed of chitosan hydrogel containing nonloaded nanocapsules (CH-NC) was also evaluat...

Journal: :Journal of Nanomedicine & Nanotechnology 2011

2015
Patricia Erebi Tawari Zhipeng Wang Mohammad Najlah Chi Wai Tsang Vinodh Kannappan Peng Liu Christopher McConville Bin He Angel L. Armesilla Weiguang Wang

The anticancer activity of disulfiram (DS) is copper(ii) (Cu)-dependent. This study investigated the anticancer mechanisms of DS/Cu using in vitro cytotoxicity and metabolic kinetic analysis. Our study indicates that DS/Cu targets cancer cells by the combination of two types of actions: (1) instant killing executed by DS/Cu reaction generated reactive oxygen species; (2) delayed cytotoxicity in...

Journal: :Environmental science. Nano 2022

Nanoencapsulation of pesticide atrazine improves efficacy. However, this study discovered adverse bioreactivity in alveolar type 1 epithelial cells (a major recipient inhaled nano-sized particles), following exposure to nanoencapsulated atrazine.

Journal: :Macromol 2023

Polyphenols have attracted attention for their anti-inflammatory, antidiabetic, and anticancer properties. Due to the antioxidant anti-inflammatory potential of these molecules, they are also proposed as a therapeutic tool prevent complications cancer decrease secondary effects conventional chemotherapeutic drugs. Nonetheless, polyphenols such flavonoids phenolic acids low bioavailability, high...

2017
Arun Kumar T. Thulasidasan Archana P. Retnakumari Mohan Shankar Vinod Vijayakurup Shabna Anwar Sanu Thankachan Kavya S. Pillai Jisha J. Pillai C. Devika Nandan Vijai V. Alex Teena Jacob Chirayil Sankar Sundaram Gopalakrishnapillai Sankaramangalam Vinod Kumar Ruby John Anto

Nanoencapsulation has emerged as a novel strategy to enhance the pharmacokinetic and therapeutic potential of conventional drugs. Recent studies from our lab have established the efficacy of curcumin in sensitizing cervical cancer cells and breast cancer cells towards paclitaxel and 5-FU chemotherapy respectively. Factors that hinder the clinical use of curcumin as a sensitizer or therapeutic a...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید