Vascularization and bone repair are accelerated by a series of gene-activated scaffolds delivering both an angiogenic and an osteogenic gene. Stem cell-mediated osteogenesis in vitro, in addition to increased vascularization and bone repair by host cells in vivo, is enhanced using all systems while the use of the nanohydroxyapatite vector to deliver both genes markedly enhances bone healing.

INTRODUCTION Hydroxyapatite (HA) is the principal inorganic constituent of human bone. Due to its good biocompatibility and osteoconductivity, all kinds of HA particles were prepared by different methods. Numerous reports demonstrated that the properties of HA affected its biological effects. METHODS Two kinds of nanohydroxyapatite with different sizes and crystallinities were obtained via a ...

This paper reports on the in vitro assessment of acid resistance characteristics mesoporous silica/nanohydroxyapatite (MSN@nHAp) biocomposite synthesized through mechanochemical method. Bovine enamel models were used to study composite ( n=5 ). X-ray diffraction and Fourier transform infrared spectroscopy...

objective(s):various methods for repairing bone defects are presented. cell therapy is one of these methods. bone marrow stromal cells (bmscs) seem to be suitable for this purpose. on the other hand, lots of biomaterials are used to improve and repair the defect in the body, so in this study we tried to produce a similar structure to the bone by the chitosan and hydroxyapatite. materials and me...

OBJECTIVES This study investigated the effects of post bleaching treatments to prevent restaining and the change of enamel surface microhardness after dental bleaching in vitro. METHODS Sixty intact human incisor teeth were stained in tea solution and randomly assigned into four groups (n=15). Then samples were bleached for two weeks (8 hours daily) by 15% carbamide peroxide. Tooth color was ...

Aim and Objectives: To compare evaluate the antibacterial efficacy of various nanoparticles incorporated in orthodontic primer with that conventional antimicrobial agents at different concentrations on Streptococcus mutans ( S. mutans) strain. Materials Methods: Transbond XT Primer was mixed 2.5% 5% benzalkonium chloride (BAC), 0.2% chlorhexidine, 1% 3% titanium dioxide (TiO 2 ) nanoparticles, ...

Galway, Ireland Development of a Collagen-Nanohydroxyapatite Gene Activated Matrix for Bone Tissue Regeneration Gráinne M Cunniffe, 2 Glenn R Dickson R, Sonia Partap, Garry P Duffy, Fergal J O’Brien, Corresponding Author: [email protected] School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, N. Ireland. Department of Anatomy, Royal College of Surgeons, Dublin, Irela...

Objective(s):Various methods for repairing bone defects are presented. Cell therapy is one of these methods. Bone marrow stromal cells (BMSCs) seem to be suitable for this purpose. On the other hand, lots of biomaterials are used to improve and repair the defect in the body, so in this study we tried to produce a similar structure to the bone by the chitosan and hydroxyapatite. Materials and Me...

Metal implant coating engineering is needed to improve the surface biocompatibility properties of metals. For this, metal surfaces with bioactive and biocompatible biomaterials will be an option. Having high as well similarity in chemical properties, nanohydroxyapatite may a candidate for implant. The key success plating formation pores which increase bioactivity In this study, was used coated ...