Nanomanipulation under scanning electron microscopy (SEM) enables direct interactions of a tool with a sample. We recently developed a nanomanipulation technique for the extraction and identification of DNA contained within sub-nuclear locations of a single cell nucleus. In nanomanipulation of sub-cellular structures, a key step is to identify targets of interest through correlating fluorescenc...

The main problem of Atomic Force Microscope (AFM) based nanomanipulation is the lack of real-time visual feedback. Although the model based visual feedback can partly solve this problem, the incorrect display caused by the uncertainties in the nano-environment often leads to a failed nanomanipulation. In this paper, a general strategy with three-level structure is proposed to overcome this prob...

Address: 1Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanociencia), Campus Universitario de Cantoblanco, Calle Faraday 9, 28049 Madrid, Spain, 2Institute of Applied Physics, Justus-Liebig Universität Giessen, Heinrich-Buff-Ring 16, 35392 Giessen, Germany, 3Department of Crystallography and Mineralogy, Complutense University of Madrid, 28040 Madrid, Spain and 4Department of E...