experiments wee performed to evaluate the contralateral effect of adjuvant induced mono arthritis. in these experiments laser doppler imaging (ldi) was used to investigate changes in blood flow. adjuvant was applied to induce chronic inflammation. temperature and knee diameter increased in the first week after administration in the administrated knee joint.substance p (sp) (a neruokinin with a ...

Background: Falciparum malaria is a severe health burden worldwide. Antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. Malarial hemozoin (HZ), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. Objective: To determine the immunological impact of hemozoin on the capacity ...

As to trial toward the elimination of Japanese encephalitis virus in natural surroundings, pigs received inoculation of inactivated Japanese encephalitis vaccine supplemented with complete Freund’s adjuvant twice at one-week interval. Effect of adjuvant supplement on the magnitude of antibody and also prevention of viremia caused by natural infection by antibody induced with vaccine were invest...

background outer membrane protein d (pd) is a highly conserved and stable protein in the outer membrane of both encapsulated (typeable) and non-capsulated (non-typeable) strains of haemophilus influenzae. as an immunogen, pd is a potential candidate vaccine against non-typeable h. influenzae (nthi) strains. objectives the aim of this study was to determine the cytokine pattern and the opsonic a...

pemphigus vulgaris (pv) is one of the most common and studied autoimmune disorders of skin. the knock down of desmogleins in the skin by igg antibodies will eventually leads to mucocutaneous problems in both genders. targeting the cardinal molecules involved in the pathways of immune response is the main goal of given therapy. with regard to the side effects of long term use of immunosuppressiv...

leishmaniasis is one of the major health problems and categorized as a class i disease (emerging and uncontrolled) by world health organization (who), causing highly significant morbidity and mortality. indeed, more than 350 million individuals are at risk of leishmania infection, and about 1.6 million new cases occur causing more than 50 thousands death annually. because of the severe toxicity...

The natural history of breast cancer has not been fully elucidated, but physicians are making progress in the treatment of patients with this disease. Randomized, controlled trials indicate that screening, adjuvant systemic therapy, and adjuvant radiotherapy can reduce the risk for death caused by breast cancer. More importantly, national statistics show that breast cancer death rates are now d...

background: falciparum malaria is a severe health burden worldwide. antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. malarial hemozoin (hz), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. objective: to determine the immunological impact of hemozoin on the capacity ...