BACKGROUND Populations in Africa mostly rely on herbal concoctions for their primarily health care, but so far scientific studies supporting the use of plants in traditional medicine remain poor. The present study was undertaken to evaluate the anti-hyperglycemic effects of Picralima nitida (seeds), Nauclea latifolia (root and stem) and Oxytenanthera abyssinica (leaves) commonly used, in diabet...

Direct effects of Nauclea latifolia extracts on different gastrointestinal nematodes of sheep is described. In vivo and in vitro studies were conducted to determine possible anthelmintic effect of leaf extracts of Nauclea latifolia toward different ovine gastro intestinal nematodes. A larval development assay was used to investigate in vitro, the effect of aqueous and ethanolic extracts of N. l...

Various combinations of Nauclea latifolia root, Artocarpus altilis stem bark, Murraya koenigii leaf and Enantia chlorantha stem bark used in African ethnomedicine as decoctions for malaria and fevers, and combinations with standard drugs, were investigated for antiplasmodial activities using Plasmodium berghei berghei-infected mice. The respective prophylactic and curative ED50 values of 189.4 ...

Nauclea latifolia (N. latifolia) and Pteleopsis suberosa (P. suberosa) are two medicinal plants used to treat several pathologies linked oxidative stress. This study aims the effects of ethanolic extracts from those on consequences cholesterolemic overload. Oxidative stress was induced by In vitro antioxidant activity evaluated using DPPH, total phenolic compounds flavonoids assays; while in vi...

Nauclea latifolia is a valuable medicinal plant for treating different ailments. Infectious diseases constitute world health concern. This work describes the phytochemical analysis and antimicrobial properties of root N. latifolia. Collected samples were extracted via cold maceration with methanol. The methanol crude extract was fractionated into n-hexane, ethyl acetate, butanol aqueous fractio...

Aqueous, ethanolic and hexane extracts of the leaves of Nauclea latifolia (Rubiaceae) were assessed for their fasting blood glucose lowering effect in normoglycaemic and streptozotocin-diabetic rats. Wistar strain albino rats were given different doses of the extracts after 18 hrs fast and their blood glucose measured at 0, 1, 2, 4 and 6 hours after treatment. The aqueous and ethanolic extracts...