نتایج جستجو برای: nct
تعداد نتایج: 1013 فیلتر نتایج به سال:
Gamma-secretase is a multiprotein, intramembrane-cleaving protease with a growing list of protein substrates, including the Notch receptors and the amyloid precursor protein. The four components of gamma-secretase complex--presenilin (PS), nicastrin (NCT), Pen2, and Aph1--are all thought to be essential for activity. The catalytic domain resides within PS proteins, NCT has been suggested to be ...
OBJECTIVE WE AIMED TO COMPARE INTRAOCULAR PRESSURE (IOP) MEASUREMENTS VIA THREE DIFFERENT TONOMETERS: the Goldmann applanation tonometer (GAT), the Tono-Pen(®) XL (TPXL), and a non-contact airpuff tonometer (NCT). METHODS This was a cross-sectional study of 200 eyes from 200 patients. Right eyes of all patients were included in this study. IOP was measured via GAT, NCT, and TPXL by three phys...
Aim : The aim of this study is to validate the efficacy of NCT by comparing its measurements with that of Goldmann’s applanation tonometry and to know if it can be used as a screening tool for glaucoma. Materials and methods : In 400 eyes of 200 adults selected for cataract surgery, IOP was measured first with NCT and 15min later with GAT and the results were compared. Results : The range of IO...
BACKGROUND Validating non-contrast-enhanced computed tomography (nCT) compared to ultrasound sonography (US) as screening method for abdominal aortic aneurysm (AAA) screening. METHODS Consecutively attending men (n = 566) from the pilot study of the randomized Danish CardioVascular Screening trial (DANCAVAS trial), underwent nCT and US examination. Diameters were measured in outer-to-outer fa...
19 Due to the constant innovations in communications tools, several educational institutions are continually evaluating the adoption of new communication tools (NCT) for their adopted learning platforms (LP). Notably, many educational institutions are interested in checking if NCT is bringing benefits in their teaching and learning process. We can state an important problem that tackles this in...
BACKGROUND Although neoadjuvant chemotherapy (NCT) is widely used, it is not clear which subgroup of locally advanced non-small-cell lung cancer (NSCLC) patients should be treated with this approach, and if a particular benefit associated with NCT exists. In this study, we aimed to investigate the potential correlates of benefit from NCT in patients with NSCLC. METHODS All randomized clinical...
Condensin is a central regulator of mitotic genome structure with mutants showing poorly condensed chromosomes and profound segregation defects. Here, we identify NCT, a complex comprising the Nrc1 BET-family tandem bromodomain protein (SPAC631.02), casein kinase II (CKII), and several TAFs, as a regulator of condensin function. We show that NCT and condensin bind similar genomic regions but on...
Simultaneous electrophysiology and confocal microscopy were used to investigate purinergic neurotransmission at single smooth muscle cells (SMCs) in mouse isolated vas deferens, and to explore the relationship between two high-resolution P2X-receptor-mediated measures of per pulse ATP release: transient peaks in the first time derivative of the rising phase of excitatory junction potentials (EJ...
PURPOSE Neoadjuvant chemotherapy (NCT) using anthracyclines and taxanes is a standard treatment for locally advanced breast cancer. Efficacy of NCT is however variable among patients and predictive markers are expected to guide the selection of patients who will benefit from NCT. A promising approach stand with polymorphisms located in genes encoding drug transporters, drug metabolizing enzymes...
CONTEXT AND OBJECTIVE Recent studies have shown noncontrast computed tomography (NCT) to be more effective than ultrasound (US) for imaging acute ureterolithiasis. However, to our knowledge, there are few studies directly comparing these techniques in an emergency teaching hospital setting. The objectives of this study were to compare the diagnostic accuracy of US and NCT performed by senior ra...
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