Neu differentiation factor (NDF, also called neuregulin) is a potent inducer of epithelial cell proliferation and has been shown to induce mammary carcinomas in transgenic mice. Notwithstanding this proliferative effect, we have shown that a novel isoform of NDF can induce apoptosis when overexpressed. Here we report that this property also extends to other NDF isoforms and that the cytoplasmic...

A previously described mathematical model, that stimulates the metabolic activities of rumen bacteria and protozoa, was used to examine the contribution of protozoa to neutral-detergent fibre (NDF) degradation in the rumen of cattle. Comparisons between predicted and experimentally observed NDF degradation showed general agreement. Further simulations were performed with diets containing variab...

Four lactating dairy cows that were ruminally and duodenally cannulated were used in an experiment with a 4 x 4 Latin square design to determine the effects of the substitution of neutral detergent fiber (NDF) from forage with NDF from wheat middlings, corn gluten feed, or a blend of distillers dried grains and hominy. Dietary crude protein and NDF averaged 18 and 31%, respectively, for the die...

Total mixed rations containing 31 or 25% NDF were supplemented with 0 or .5 kg/cow per d Ca salts of fatty acids to study the effect of adding Ca salts of fatty acids to diets that differed in NDF content. Rations were fed for ad libitum intake to 12 early to midlactation Holstein cows in a replicated 4 x 4 Latin square design with a 2 x 2 factorial arrangement of treatments. No significant int...

Nondermatophytic filamentous fungi (NDF) other than Scytalidium species are variously said to cause between 0 and 50% of all toenail onychomycoses, though most estimates are in the 2-5% range. Due to the difficulty of obtaining 'gold standard' control data for comparison, the accuracy of many laboratory evaluation processes used to deal with potential NDF onychomycoses has never been rigorously...

take potential (Van Soest, 1994). The concentration of NDF is heritable in several forage species, and rates of gain Voluntary intake is generally considered to be the single most from selection for reduced NDF concentration of herbimportant factor limiting animal performance on high-forage diets. Neutral detergent fiber (NDF) is the laboratory variable most closely age are reported to be as hi...

Voluntary intake of forage by ruminants is limited by forage bulk density and the rate at which forage is degraded to particles that can pass from the rumen. Two indirect laboratory measures of intake, neutral detergent ®ber (NDF) concentration and particle-size reduction index (PSRI), are being used in plant breeding programs. The objective of this study was to determine the relationship among...

Corn silage with high NDF concentration has the potential to reduce DMI because it has a greater filling effect in the rumen than low-NDF corn silage. Our objective was to determine whether ruminal fill influences DMI to the same extent with low- or high-NDF corn silage-based diets. Eight ruminally cannulated Holstein steers (198 +/- 13 kg) were randomly assigned to a 2 x 2 factorial arrangemen...

Total mixed ration (TMR) samples (n = 110) were analyzed for dry matter (DM), crude protein (CP), soluble CP, neutral detergent fiber (NDF), NDF CP, starch, ash, fat, total ethanol-soluble carbohydrate, and nonfiber carbohydrate (NFC). Rapidly and slowly degraded and undegraded in situ CP fractions and in vitro DM, organic matter, and NDF digestibility were determined on each TMR. The TMR were ...