to study inheritance of resistance to septoria tritici blotch in wheat, the generation mean analysis method was used. so six generations (p1, p2, f1, f2, bc1 and bc2) were planted under completely randomized design with three replications in greenhouse. seedlings were inoculated at the second-leaf stage with an isolate of septoria tritici and necrosis and picnidia density and area under disease...

PURPOSE To correlate intra voxel incoherent motion (IVIM) diffusion parameters of liver parenchyma and hepatocellular carcinoma (HCC) with degree of liver/tumor enhancement and necrosis; and to assess the diagnostic performance of diffusion parameters vs. enhancement ratios (ER) for prediction of complete tumor necrosis. PATIENTS AND METHODS In this IRB approved HIPAA compliant study, we incl...

Protein thermal stability is important for therapeutic proteins, both influencing the pharmacokinetic and pharmacodynamic properties and for stability during production and shelf-life of the final product. In this paper we show the redesign of a therapeutically interesting trimeric all-beta-sheet protein, the cytokine TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), yielding var...

To obtain more representative biopsy specimens in glioblastoma, we performed multiple stereotactic biopsies of active tumor and necrosis. We investigated their pathologic differences of diagnosis and also examined the pathologic features that varied with 11C-methionine uptake on PET. From December 2009 to October 2010, we performed stereotactic bi...

BACKGROUND Nipple sparing mastectomy (NSM) can be performed for prophylactic mastectomy and the treatment of selected breast cancer with oncologic safety. The risk of skin and nipple necrosis is a frequent complication of NSM procedure, and it is usually related to surgical technique. However, the role of the breast morphology should be also investigated. METHOD We prospectively performed an ...

Myocardial infarction after coronary artery bypass graft (CABG) surgery has been described clinically in up to 30% of patients but there is little morphologic information about the character and pathogenesis of this myocardial injury. We studied myocardium in the distribution of bypassed and nonbypassed coronary arteries for the presence of contraction band necrosis as compared to coagulation n...

In chronic hepatitis, pathologies reveal a prominent inflammatory infiltrate portal consisting mostly of lymphocytes and plasma cells invading the portal spaces, although one can also identify macrophages, neutrophils or eosinophils. In all the forms of chronic hepatitis, fibrosis starts in the portal area, namely periportally, subsequently extends towards the lobules to the central veins, caus...

This study aimed to obtain the main active components of Xianling Gubao capsule and identify their pharmacological characteristics mechanism action in treatment steroid-induced femoral head necrosis. The chemical constituents direct targets were obtained by system pharmacology platform traditional Chinese medicine. GeneCards database gene expression omnibus used pathogenic genes related Through...