نتایج جستجو برای: necrotic myositis

تعداد نتایج: 21099  

2017
Lina Renström Per Stål Yafeng Song Sture Forsgren

BACKGROUND TNF-alpha is suggested to be involved in muscle damage and muscle inflammation (myositis). In order to evaluate whether TNF-alpha is involved in the myositis that occurs in response to muscle overuse, the aim was to examine the expression patterns of TNF receptors in this condition. METHODS A rabbit muscle overuse model leading to myositis in the soleus muscle was used. The express...

Journal: :Brain : a journal of neurology 1997
K Sivakumar C Semino-Mora M C Dalakas

We describe the occurrence of an inflammatory inclusion body myositis in siblings of a single generation in three separate families. The disease in this total of seven patients was characterized by selective and early involvement of forearm and finger flexors, confirmed by MRI, and weakness of the quadriceps, triceps and foot extensors. Muscle biopsies in at least two members from each family s...

2018

Pulmonary: asthma, pneumonitis and haemoptysis. Upper respiratory tract: allergic rhinitis, paranasal sinusitis, nasal polyposis. Cardiac involvement is common. [6]This includes heart failure, myocarditis and myocardial infarction. [7] Skin: purpura, skin nodules, leukocytoclastic angiitis with palpable purpura, livedo reticularis, urticaria, necrotic bullae and digital ischaemia. Renal: glomer...

Journal: :The Journal of infectious diseases 2014
Nischay Mishra Marcus Pereira Roy H Rhodes Ping An James M Pipas Komal Jain Amit Kapoor Thomas Briese Phyllis L Faust W Ian Lipkin

BACKGROUND A 33 year-old pancreatic transplant recipient developed weakness, retinal blindness, and necrotic plaques on her face, scalp, and hands. METHODS A muscle biopsy was analyzed by light and electron microscopy and high-throughput nucleic acid sequencing. RESULTS The biopsy revealed microthrombosis and viral particles in swollen endothelial cell nuclei. High-throughput sequencing of ...

2011
Tohru Kimura

Partial changes of color (greenish to brownish) were found in prime marbled beef of Japanese black cattle. The disseminated lesions of the skeletal muscles were histopathologically examined in relation to Sarcocystis infection. The lesions in the muscles showed granulomas with inflammatory cell infiltration. The sarcocysts had a distinct wall, which was radically striated by palisading villar p...

2012
Mazen M. Dimachkie Richard J. Barohn

Sporadic inclusion body myositis (IBM) is the most common idiopathic inflammatory myopathy (IIM) after age 50 years. It presents with chronic insidious proximal leg and distal arm asymmetric muscle weakness. Despite similarities with polymyositis (PM), it is likely that IBM is primarily a degenerative disorder rather than inflammatory muscle disease. IBM is associated with a modest degree of cr...

Journal: :Brain : a journal of neurology 2012
Jens Schmidt Konstanze Barthel Jana Zschüntzsch Ingrid E Muth Emily J Swindle Anja Hombach Stephan Sehmisch Arne Wrede Fred Lühder Ralf Gold Marinos C Dalakas

Sporadic inclusion body myositis is a severely disabling myopathy. The design of effective treatment strategies is hampered by insufficient understanding of the complex disease pathology. Particularly, the nature of interrelationships between inflammatory and degenerative pathomechanisms in sporadic inclusion body myositis has remained elusive. In Alzheimer's dementia, accumulation of β-amyloid...

2017
E. L. Binns E. Moraitis S. Maillard S. Tansley N. McHugh T. S. Jacques L. R. Wedderburn C. Pilkington S. A. Yasin K. Nistala Kate Armon Joe Ellis-Gage Holly Roper Vanja Briggs Joanna Watts Liza McCann Ian Roberts Eileen Baildam Louise Hanna Olivia Lloyd Susan Wadeson Phil Riley Ann McGovern Clive Ryder Janis Scott Beverley Thomas Eslam Al-Abadi Sue Wyatt Gillian Jackson Tania Amin Mark Wood Vanessa Van Rooyen Deborah Burton Joyce Davidson Janet Gardner-Medwin Neil Martin Sue Ferguson Liz Waxman Michael Browne Mark Friswell Helen Foster Alison Swift Sharmila Jandial Vicky Stevenson Debbie Wade Ethan Sen Eve Smith Lisa Qiao Stuart Watson Claire Duong Helen Venning Rangaraj Satyapal Elizabeth Stretton Mary Jordan Ellen Mosley Anna Frost Lindsay Crate Kishore Warrier Stefanie Stafford Lucy Wedderburn Clarissa Pilkington Nathan Hasson Sue Maillard Elizabeth Halkon Virginia Brown Audrey Juggins Sally Smith Sian Lunt Elli Enayat Hemlata Varsani Laura Kassoumeri Laura Beard Katie Arnold Yvonne Glackin Stephanie Simou Beverley Almeida Kiran Nistala Raquel Marques Claire Deakin Stefanie Dowle Charis Papadopoulou Cerise Johnson-Moore Emily Robinson Kevin Murray John Ioannou Linda Suffield Muthana Al-Obaidi Helen Lee Sam Leach Helen Smith Anne-Marie McMahon Heather Chisem Ruth Kingshott Nick Wilkinson Emma Inness Eunice Kendall David Mayers Ruth Etherton Danielle Miller Kathryn Bailey Jacqui Clinch Natalie Fineman Helen Pluess-Hall Lindsay Vallance Louise Akeroyd Alice Leahy Amy Collier Rebecca Cutts Emma Macleod Hans De Graaf Brian Davidson Sarah Hartfree Danny Pratt

BACKGROUND Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to respond to conventional first line therapies. We present three cases where remission was successfully induced using combination therapy with intensive rehabilitation. CASE PRES...

Journal: :iranian journal of pathology 2012
etrat javadi rad azadeh almasi behzad khoshraftar

we describe a rare case of laryngeal fasciitis ossificans. a 58-year-old man presented with hoarseness and a nodule was found in the larynx. excisional biopsy was performed, and follow-up laryngoscopy showed complete resolution of this reactive lesion, and normal laryngeal function. the 0.6 cm diameter nodule was well circumscribed and histologically, the lesion was composed of uniform woven bo...

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