نتایج جستجو برای: neoadjuvant chemoradiation

تعداد نتایج: 18874  

2015
Raquel Conde-Muíño Marta Cuadros Natalia Zambudio Inmaculada Segura-Jiménez Carlos Cano Pablo Palma

There has been a high local recurrence rate in rectal cancer. Besides improvements in surgical techniques, both neoadjuvant short-course radiotherapy and long-course chemoradiation improve oncological results. Approximately 40-60% of rectal cancer patients treated with neoadjuvant chemoradiation achieve some degree of pathologic response. However, there is no effective method of predicting whic...

2016
Kittinut Timudom Natthawut Phothong Thawatchai Akaraviputh Vitoon Chinswangwatanakul Ananya Pongpaibul Janjira Petsuksiri Suthinee Ithimakin Atthaphorn Trakarnsanga

Background. Traditionally, rectal cancer surgery is recommended 6 to 8 weeks after completing neoadjuvant chemoradiation. Extending the waiting time may increase the tumor response rate. However, the perioperative complication rate may increase. The purpose of this study was to determine the association between extending the waiting time of surgery after neoadjuvant chemoradiation and periopera...

Journal: :Cancer 2012
Jeannelyn S Estrella Asif Rashid Jason B Fleming Matthew H Katz Jeffrey E Lee Robert A Wolf Gauri R Varadhachary Peter W T Pisters Eddie K Abdalla Jean-Nicolas Vauthey Hua Wang Henry F Gomez Douglas B Evans James L Abbruzzese Huamin Wang

BACKGROUND Neoadjuvant chemoradiation before surgery is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC). However, analysis of prognostic factors is limited for patients with PDAC treated with neoadjuvant chemoradiation and pancreaticoduodenectomy (PD). METHODS The study population was comprised of 240 consecutive patients with PDAC who received neoadjuvant chemoradi...

A MOUSAVI, M GOLNAVAZ, M MODARES, N BEHTASH,

Tumor size seems to be a determinant in the prognosis of early cervical cancer. Patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' The purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (NArC) programs followed by radical hysterectomy in stage Ib - lIb bulky cervical cancer. From September ...

بابایی, محمد , حداد, پیمان , عقیلی, مهدی , علی‌خاصی, افسانه , فاضلی, محمد صادق , فرهان, فرشید , مداح صفایی, افسانه , میرایی آشتیانی, منیر سادات ,

Background: This study investigated compatibility between post chemoradiation magnetic resonance images and histologic findings after operation and chemoradiation in patients with locally advanced rectal cancer. Methods: In this prospective study, 63 patients referred to Cancer Institute of Emam Khomeini Hospital, Tehran, Iran, from October 2011 to October 2013 with locally advanced rectal c...

Journal: :Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2006
Masayuki Shinoda Shunzo Hatooka Shoichi Mori Tetsuya Mitsudomi

Radical resection has been considered the only possible way to save the lives of patients with esophageal cancer. Therefore, tremendous efforts have been made in order to improve the surgical results for resectable locoregional esophageal cancer. Various surgical approaches have been developed. Combination therapies such as neoadjuvant, adjuvant chemotherapy, and neoadjuvant chemoradiation have...

Journal: :Annals of the Academy of Medicine, Singapore 2014
Yiat Horng Leong Cheng Nang Leong Guan Sze Tay Richard Sim Gilberto Lopes Wilson Low Bok Ai Choo Jeremy Tey

INTRODUCTION This study reports the outcomes of patients with locally advanced rectal cancer treated with neoadjuvant chemoradiation followed by surgery in a local population of Singapore. MATERIALS AND METHODS The records of 85 patients who underwent neoadjuvant chemoradiation for locally advanced rectal cancer followed by surgery at the Tan Tock Seng Hospital (TTSH) between November 2002 an...

Journal: :Journal of the National Comprehensive Cancer Network : JNCCN 2012
John G Phillips Theodore S Hong David P Ryan

Because patients with locally advanced rectal cancer are at high risk for both recurrence and distant disease, they require adjuvant therapy. In the United States, the current standard of care is neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy. Neoadjuvant chemoradiation has been shown to improve local recurrence rates and decrease toxicity. However in the era of total ...

2017
Brendan F Scully C. Randall Cooper Steven A Lee-Kong

The standard treatment for locally advanced rectal cancer is neoadjuvant chemoradiation followed by radical proctectomy with total mesorectal excision. A significant percentage of patients exhibit a pathological complete response with associated survival benefit. The management of patients who exhibit a complete clinical response after neoadjuvant chemoradiation, and could potentially avoid maj...

2013
Won-Suk Lee Seok Ho Lee Jeong-Heum Baek Woon Kee Lee Jung Nam Lee Na Rae Kim Yeon Ho Park

BACKGROUND The effect of insufficient node sampling in patients with rectal cancer managed by neoadjuvant chemoradiation followed by surgery has not been clearly determined. We evalulated the impact of insufficient sampling or even abscence of lymph nodes in the specimen on survival in patients at high-risk (T3, T4 or node positive) for rectal cancer. METHODS We conducted a single institution...

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