A case of adult nephroblastoma in a 51-year-old woman is reported. A percutaneous aspiration biopsy did not lead to the right diagnosis presumably because the histologic structure of the tumour consisted exclusively of more or less differentiated epithelial-like elements, while mesenchymal tumour components were not demonstrated. It is concluded that this type of nephroblastoma, resembling a re...

OBJECTIVE To study the influence of curcumin on chemosensitivity of nephroblastoma cells. METHODS Human nephroblastoma cells line SK-NEP-1 was transplanted to the nude mice subcutaneously to establish the implantation tumor model of human nephroblastoma cells. A total of 30 tumor-bearing mice were divided into three groups of ten randomly. The routine chemotherapy group was given vincristine ...

RATIONALE Teratoma with nephroblastoma is a rare disease. The most common site at which teratoma with nephroblastoma occurs is the kidney. The mechanisms underlying the development of teratoma with nephroblastoma have not been fully elucidated. PATIENT CONCERNS In the current report, we describe the clinical characteristics of a 3-year-old girl with a complaint of a painless abdominal mass in...

There are two main widely accepted prognostic factors in nephroblastoma group of tumors--histological type of tumor and clinical stage of disease. However nuclear anaplasia, one of the elements of Wilms' tumor microscopic picture was found as a new prognostic marker in this group of tumors. Estimation of nuclear anaplasia is an obligatory procedure in currently used therapeutic protocols. In ou...

Embryonal cancers are a heterogeneous group of rare cancers which mainly occur in children and adolescents. The aim of the present study was to estimate the burden (incidence, prevalence, survival and proportion of cured) for the principal embryonal cancers in Europe (EU27), using population-based data from cancer registries (CRs) participating in RARECARE. We identified 3322 cases diagnosed fr...

The paper describes a novel approach to investigating Wilms' tumour (nephroblastoma) biology at the atomic level. Isotope Ratio Mass Spectrometry (IRMS) was used to directly assess the isotope ratios of nitrogen and carbon in 84 Wilms' tumour tissue samples from 28 cases representing the histological spectrum of nephroblastoma. Marked differences in nitrogen and carbon isotope ratios were found...

Wilms’ tumor (nephroblastoma) is a malignant renal tumor that arises from abnormal proliferation of metanephric blastema without differentiation into glomeruli and tubules. It is the most common malignant kidney tumor in children and accounts for 6% of all childhood malignancies. Nephroblastoma is a very rare tumor in the adult age group. Only 3% off all Wilms’ tumors are diagnosed in age over ...

Nephroblastoma is one of the most common causes of abdominal-pelvic mass in children. It still raises a diagnostic problem because of the wide variety of causes of abdominal-pelvic mass but also because of the delays in consultation in sub-Saharan black Africa and consequently the discovery of the mass at a very late and sometimes metastatic stage. Yet nephroblastoma is a very chemo-sensitive m...