نتایج جستجو برای: neurodegeneration with brain iron accumulation

تعداد نتایج: 9480785  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Jason D Surratt Arthur W H Chan Nathan C Eddingsaas ManNin Chan Christine L Loza Alan J Kwan Scott P Hersey Richard C Flagan Paul O Wennberg John H Seinfeld

Isoprene is a significant source of atmospheric organic aerosol; however, the oxidation pathways that lead to secondary organic aerosol (SOA) have remained elusive. Here, we identify the role of two key reactive intermediates, epoxydiols of isoprene (IEPOX = beta-IEPOX + delta-IEPOX) and methacryloylperoxynitrate (MPAN), which are formed during isoprene oxidation under low- and high-NO(x) condi...

Journal: :The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2010
Kirsty Kiezebrink Evleen T Mann Sarah R Bujac Michael J Stubbins David A Campbell John E Blundell

OBJECTIVES There is mixed evidence of association of serotoninergic genes with anorexia nervosa (AN), but substantial evidence for the involvement of serotonergic mechanisms in appetite control. This study was designed to investigate possible associations between the two subtypes of AN (Restricting-RAN, and Binge-purging-BPAN) and polymorphisms within five genes encoding for proteins involved i...

2004
Jane K Seale

The 2001 Special Educational Needs and Disability Act (SENDA, 2001) made it an offence for educational institutions in the UK to discriminate against a disabled person by treating him or her less favourably than others for a reason relating to their disability. Learning technologists have therefore been charged with the responsibility of ensuring that electronic teaching materials can be access...

Journal: :Brain : a journal of neurology 2011
Michael C Kruer Mark Hiken Allison Gregory Alessandro Malandrini David Clark Penny Hogarth Marjorie Grafe Susan J Hayflick Randall L Woltjer

Pantothenate kinase-associated neurodegeneration is a form of neurodegeneration with brain iron accumulation, characterized by a progressive movement disorder and prominent iron deposition in the globus pallidus. Formerly referred to as Hallervorden-Spatz syndrome, the disorder was renamed pantothenate kinase-associated neurodegeneration after discovery of the causative gene, PANK2. Although th...

Journal: :Archives of neurology 2007
George K Tofaris Tamas Revesz Thomas S Jacques Savvas Papacostas Jeremy Chataway

BACKGROUND Neurodegeneration with brain iron accumulation is a rare neurodegenerative disorder characterized by iron deposition in the basal ganglia and neuroaxonal dystrophy. Familial cases with mutations in the pantothenate kinase gene are associated with a specific phenotype. In contrast, sporadic cases are heterogeneous in their clinical presentation. OBJECTIVE To describe an atypical cas...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید