The effective identification of neurodevelopmental disorders is essential for early diagnosis and provision of intervention services. For many of these conditions, one of the primary domains of abnormality is language development. This review addresses what is known about the earliest indicators of language impairment across a range of neurodevelopmental disorders; consideration is given to bot...

objective neurodevelopmental disability is one of the most common problems of children referred to  pediatric neurology clinics. these children may suffer from speech delay, intellectual deficiency and behavioral disorder. some patients with neurodevelopomental delay, especially those with intellectual disability and speech problems, have abnormal electroencephalograms, without clinical seizure...

High and increasing prevalence of neurodevelopmental disorders place enormous personal and economic burdens on society. Given the growing realization that the roots of neurodevelopmental disorders often lie in early childhood, there is an urgent need to identify childhood risk factors. Neurodevelopment is marked by periods of heightened experience-dependent neuroplasticity wherein neural circui...

Very low birth weight is associated with long term neurodevelopmental complications. Macroscopic brain abnormalities in prematurity survivors have been investigated in several studies. However, there is limited data regarding local cerebral metabolic status and neurodevelopmental outcomes. The purpose of this study was to characterize the relationship between proton magnetic resonance spectra i...

OBJECTIVE The purpose of this study is to determine the frequency of emotional, behavioral, and learning disorders in children exposed in utero to hyperemesis gravidarum (HG) and to identify prognostic factors for these disorders. STUDY DESIGN Neurodevelopmental outcomes of 312 children from 203 mothers with HG were compared to neurodevelopmental outcomes from 169 children from 89 unaffected ...

the human brain is composed of several interconnected, functionally distinct structures and much debate has surrounded the basic question of how these structures evolve. brain development begins in early gestation. between 4 weeks and 9 months, brain undergoes rapid development. there are six stages of nervous system development. brain increases connections between birth and 21 years of age. ab...

Measuring biomarkers to predict or identify illness is a strategy that is increasingly used in many fields, including in the field of psychiatry and neurodevelopmental disorders [1-3]. The United States Food and Drug Administration (FDA) define a biomarker as an objective measurement of a normal or pathologic biological process, or an objective measurement that indicates response to a treatment...