Nearly 70 years after the discovery of penicillin, neurologic infectious diseases (NIDs) remain an important worldwide source of morbidity and mortality. The clinician faced with a potential NID must urgently consider patient demographics, pace of illness and clinical syndrome, and laboratory data. In keeping with the topics of this issue, initial emergency diagnosis and management are emphasiz...

The term paraneoplastic neurologic disease (PND) encompasses several degenerative central or peripheral nervous system disorders that result from indirect effects of systemic cancer on elements of the nervous system. By definition, the dysfunction does not result from invasion or metastasis by tumor. The concept of a remote or indirect effect of cancer on the nervous system arose in the latter ...