A soft tissue's macroscopic behavior is largely determined by its microstructural components (often a collagen fiber network surrounded by a nonfibrillar matrix (NFM)). In the present study, a coupled fiber-matrix model was developed to fully quantify the internal stress field within such a tissue and to explore interactions between the collagen fiber network and nonfibrillar matrix (NFM). Voro...

5-Hydroxy-2-pyridone (2,5-DHP) is a central metabolic intermediate in catabolism of many pyridine derivatives, and has been suggested as a potential carcinogen. 2,5-DHP is frequently transformed to N-formylmaleamic acid (NFM) by a 2,5-DHP dioxygenase. Three hypotheses were formerly discussed for conversion of 2,5-DHP to maleamate. Based on enzymatic reactions of dioxygenase (Hpo) and N-formylam...

Responses of the northern fowl mite (NFM), Ornithonyssus sylviarum (Canestrini & Fanzago) (Acari: Macronyssidae), and the chicken body louse (CBL), Menacanthus stramineus (Nitzsch) (Phthiraptera: Menoponidae), to variation in temperature, light, and humidity were assessed in bioassays. The location on a continuous thermal gradient atwhich each ectoparasite arrested was recorded and analyzed. NF...

Automated methods of neonatal EEG seizure detection attempt to highlight the evolving, stereotypical, pseudo-periodic, nature of EEG seizure while rejecting the nonstationary, modulated, coloured stochastic background in the presence of various EEG artefacts. An important aspect of neonatal seizure detection is, therefore, the accurate representation and detection of pseudo-periodicity in the n...

The null-field method with discrete sources (NFM-DS) is used for the simulation of the light scattering by elongated particles. These particles can be decomposed into several identical parts with a small aspect ratio. The T-matrix computed for a single part is used to compose the T-matrix for the whole particle. For verification purposes the light scattering distributions computed with NFM-DS a...

In previous work (Wilson forthcoming), I have endorsed an account of the physical according to which an entity is physical just in case it is (approximately accurately) treated by current or future (in the limit of inquiry, ideal) physics, and is not fundamentally mental. Call this account of the physical the physics-based NFM (“no fundamental mentality”) account. The physics-based NFM account ...

Neurofilaments (NFs), the major intermediate filaments of central nervous system (CNS) and peripheral nervous system (PNS) neurons, are heteropolymers formed from the high (NFH), middle (NFM), and low (NFL) molecular weight NF subunits. To gain insights into how the expression of NF subunit proteins is regulated in vivo, two transgenes harboring coding sequences for human NFM (hNFM) with or wit...

PURPOSE To demonstrate the presence of corneal stromal precursors that express neural markers in vitro. METHODS To isolate sphere-forming cells, human corneal stromal cells were subjected to a reaggregation-free neurosphere assay in medium containing methylcellulose gel matrix. To promote differentiation, the isolated sphere colonies were plated in wells with medium containing fetal bovine se...

First posted July 10, 2023 For additional information, contact: Water Mission AreaU.S. Geological Survey12201 Sunrise Valley DriveReston, VA 20192Email: [email protected] The “National Field Manual for the Collection of Water-Quality Data” (NFM) provides guidelines and procedures U.S. Survey (USGS) personnel who collect data used to assess quality Nation’s surface-water groundwater resources. This c...

Myeloperoxidase (MPO) is an important enzyme that catalyzes the reaction between hydrogen peroxide and chloride to generate hypochlorous acid, which oxidizes a range of biomolecules and has been associated with inflammatory diseases. The synthetic compounds N-phenylmaleimide (NFM) and 4-methyl-N-phenylmaleimide (Me-NFM) increased the MPO activity in vitro (of isolated enzyme and in isolated cel...