ABSTRACT The cosmic near-infrared background (NIRB) offers a powerful integral probe of radiative processes at different epochs, including the pre-reionization era when metal-free, Population III (Pop III) stars first formed. While radiation from metal-enriched, II II) likely dominates contribution to observed NIRB reionization era, Pop – if formed efficiently might leave characteristic imprint...

background anaerobic-inducible promoters are alternatives of chemical-inducible promoters for expression of recombinant proteins especially in conditions where chemical induction is not possible or anaerobic conditions are preferable. the nirb promoter is the promoter of the first gene of nir operon in escherichia coli, which encodes nadh-dependent nitrite reductase. this promoter is naturally ...

Attenuated Salmonella enterica serovar Typhimurium has been used for targeted delivery of recombinant antigens to the gut-associated lymphoid tissues. One potential problem associated with this vaccine approach is the likelihood of in vivo instability of the plasmid constructs caused by constitutive hyperexpression of the heterologous immunogen. The aim of this study was to generate and charact...

The context of this paper is the simulation parameter-dependent partial differential equations (PDEs). When aim to solve such PDEs for a large number parameter values, Reduced Basis Methods (RBM) are often used reduce computational costs classical high fidelity code based on Finite Element Method (FEM), Volume (FVM) or Spectral methods. efficient implementation most these RBM requires modify co...

Activation of receptor tyrosine kinase (RTK) signalling pathways is frequently correlated to cancer cell proliferation, angiogenesis and cell survival. Sprouty (SPRY) proteins function as a physiological endogenous inhibitor of RTK signalling pathways, have been shown to be deregulated in most cancer cells. Here, we demonstrated that over-expression of SPRY1 and SPRY2 inhibited B16F10 cell prol...

In Escherichia coli, nitrosative mutagenesis may occur during nitrate or nitrite respiration. The endogenous nitrosating agent N2O3 (dinitrogen trioxide, nitrous anhydride) may be formed either by the condensation of nitrous acid or by the autooxidation of nitric oxide, both of which are metabolic by-products. The purpose of this study was to determine which of these two agents is more responsi...

The redshifted light of the first (Pop III) stars might substantially contribute to the near infrared background (NIRB). By fitting recent data with models including upto-date Pop III stellar spectra, we find that such stars can indeed account for the whole NIRB residual (i.e. after ‘normal’ galaxy contribution subtraction) if the high redshift star formation efficiency is f⋆ = 10% − 50%, depen...

Archaea are widespread in extreme and temperate environments, and cultured representatives cover a broad spectrum of metabolic capacities, which sets them up for potentially major roles in the biogeochemistry of their ecosystems. The detection, characterization, and quantification of archaeal functions in mixed communities require Archaea-specific primers or probes for the corresponding metabol...

The NarX and NarQ sensor-histidine kinases control phosphorylation of the NarL and NarP response regulators in response to the respiratory oxidants nitrate and nitrite. Target operon transcription is activated by the Fnr protein in response to anaerobiosis, and it is further activated and/or repressed by the phospho-NarL and phospho-NarP proteins, which bind to heptamer DNA sequences. The locat...

UNLABELLED Nitrate is widely used as a nitrogen source by cyanobacteria, in which the nitrate assimilation structural genes frequently constitute the so-called nirA operon. This operon contains the genes encoding nitrite reductase (nirA), a nitrate/nitrite transporter (frequently an ABC-type transporter; nrtABCD), and nitrate reductase (narB). In the model filamentous cyanobacterium Anabaena sp...