نتایج جستجو برای: nms

تعداد نتایج: 1346  

Journal: :The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2016
Fang Ba Mona Obaid Marguerite Wieler Richard Camicioli W R Wayne Martin

BACKGROUND Parkinson disease (PD) presents with motor and non-motor symptoms (NMS). The NMS often precede the onset of motor symptoms, but may progress throughout the disease course. Tremor dominant, postural instability gait difficulty (PIGD), and indeterminate phenotypes can be distinguished using Unified PD Rating scales (UPDRS-III). We hypothesized that the PIGD phenotype would be more like...

2015
Hye Mi Lee Seong-Beom Koh

Parkinson's disease (PD) is a multi-systemic disorder that is characterized by a combination of motor and non-motor symptoms (NMS). The dopaminergic neurodegeneration of PD is involved in the genesis of NMS, but other conditions and side effects of levodopa are also associated with NMS. NMS can develop at all stage of PD and rapid eyeball movement sleep behavior disorder (RBD), constipation, de...

2015
Martino Belvederi Murri Argentina Guaglianone Michele Bugliani Pietro Calcagno Matteo Respino Gianluca Serafini Marco Innamorati Maurizio Pompili Mario Amore

BACKGROUND Neuroleptic malignant syndrome (NMS) is a rare, severe, idiosyncratic adverse reaction to antipsychotics. Second-generation antipsychotics (SGAs) were originally assumed to be free from the risk of causing NMS, however several cases of NMS induced by SGAs (SGA-NMS) have been reported. OBJECTIVES The aim of this study was to systematically review available studies and case reports o...

Journal: :British Journal of Psychiatry 1991

2016
Jun Kyu Mun Jinyoung Youn Jin Whan Cho Eung-Seok Oh Ji Sun Kim Suyeon Park Wooyoung Jang Jin Se Park Seong-Beom Koh Jae Hyeok Lee Hee Kyung Park Han-Joon Kim Beom S. Jeon Hae-Won Shin Sun-Ah Choi Sang Jin Kim Seong-Min Choi Ji-Yun Park Ji Young Kim Sun Ju Chung Chong Sik Lee Tae-Beom Ahn Won Chan Kim Hyun Sook Kim Sang Myung Cheon Jae Woo Kim Hee-Tae Kim Jee-Young Lee Eun-Joo Kim Jong-Min Kim Kwang Soo Lee Joong-Seok Kim Min-Jeong Kim Jong Sam Baik Ki-Jong Park Hee Jin Kim Mee Young Park Ji Hoon Kang Sook Kun Song Yong Duk Kim Ji Young Yun Ho-Won Lee In-Uk Song Young H. Sohn Phil Hyu Lee Jeong-Ho Park Hyung Geun Oh Kun Woo Park Do-Young Kwon

Despite the clinical impact of non-motor symptoms (NMS) in Parkinson's disease (PD), the characteristic NMS in relation to the motor subtypes of PD is not well elucidated. In this study, we enrolled drug-naïve PD patients and compared NMS between PD subtypes. We enrolled 136 drug-naïve, early PD patients and 50 normal controls. All the enrolled PD patients were divided into tremor dominant (TD)...

Journal: :Endocrinology 2007
E Vigo J Roa M López J M Castellano R Fernandez-Fernandez V M Navarro R Pineda E Aguilar C Diéguez L Pinilla M Tena-Sempere

Neuromedin S (NMS), a 36 amino acid peptide structurally related to neuromedin U, was recently identified in rat brain as ligand for the G protein-coupled receptor FM4/TGR-1, also termed neuromedin U receptor type-2 (NMU2R). Central expression of NMS appears restricted to the suprachiasmatic nucleus, and NMS has been involved in the regulation of dark-light rhythms and suppression of food intak...

2017
Siddharth Sarkar Nitin Gupta

Neuroleptic malignant syndrome (NMS) is a rare but potentially fatal adverse event associated with the use of antipsychotics. Although atypical antipsychotics were initially considered to carry no risk of NMS, reports have accumulated over time implicating them in NMS causation. Almost all atypical antipsychotics have been reported to be associated with NMS. The clinical profile of NMS caused b...

1997
P. John Alexander Ranji Mathai Thomas

Whether there is an increased risk of occurrence of neuroleptic malignant syndrome (NMS) on combined treatment with lithium and neuroleptic is a controversial issue. Patients seen in a general psychiatry unit of a university hospital in India were prospectively screened for NMS over a 2 year period. Diagnosis of NMS was made on operational criteria and the details of treatment at the time of oc...

2010
Frédéric S. Dumont Richard Kinkead

Neonatal maternal separation (NMS) is a form of stress which disrupts respiratory control development. Awake adult male rats previously subjected to NMS show a ventilatory response to hypercapnia (HCVR; FICO2 = 0.05) 47% lower than controls; however, the underlying mechanisms are unknown. To address this issue, we first tested the hypothesis that carotid bodies contribute to NMS-related attenua...

2015
Fahd Baig Michael Lawton Michal Rolinski Claudio Ruffmann Kannan Nithi Samuel G. Evetts Hugo R. Fernandes Yoav Ben‐Shlomo Michele T.M Hu

Nonmotor symptoms (NMS) are an important prodromal feature of Parkinson's disease (PD). However, their frequency, treatment rates, and impact on health-related quality of life (HRQoL) in the early motor phase is unclear. Rates of NMS in enriched at-risk populations, such as first-degree PD relatives, have not been delineated. We assessed NMS in an early cohort of PD, first-degree PD relatives a...

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