نتایج جستجو برای: no2 0047 333 00912 391 194

تعداد نتایج: 23615  

Journal: :Physiological reviews 1969
R E Smith B A Horwitz

Historical Background. ..................................................... 330 PhylogeneticDistribution .................................................. 332 AnatomyandTopology ................................................... 333 Vasculature of Brown Adipose Tissue. ...................................... 338 Microcirculation and vascularity .......................................... 338 G...

2013
Suzanne Lesage Isabelle Le Ber Christel Condroyer Emmanuel Broussolle Audrey Gabelle Stéphane Thobois Florence Pasquier Karl Mondon Patrick A. Dion Daniel Rochefort Guy A. Rouleau Alexandra Dürr Alexis Brice

1 Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l’Institut du Cerveau et de la Moelle épinière, UMR-S975; Inserm, U975, CNRS, UMR 7225, 75013 Paris, France 2 Centre national de référence des démences rares, 75013 Paris, France 3 Université Lyon I; Centre de Neurosciences Cognitives, CNRS UMR5229; Service de Neurologie C, Hôpital Neurologique Pierre Wertheimer, 69500 Bron, Fra...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Amanda Obaidat Jeffrey Weiss Brett Wahlgren Rama R Manam Venkat R Macherla Katherine McArthur Ta-Hsiang Chao Michael A Palladino G Kenneth Lloyd Barbara C Potts Salvatore J Enna Saskia T C Neuteboom Bruno Hagenbuch

The present study was undertaken to compare the cellular transport characteristics of [(3)H]NPI-0052 (1R,4R,5S)-4-(2-chloroethyl)-1-((S)-((S)-cyclohex-2-enyl)(hydroxy)methyl)-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione (marizomib; salinosporamide A) and [(3)H]NPI-0047 (1R,4R, 5S)-1-((S)-((S)-cyclohex-2-enyl)(hydroxy)methyl)-4-ethyl-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione in ...

Journal: :Elementa 2021

We present a novel source attribution approach that incorporates satellite data into GEOS-Chem adjoint simulations to characterize the species-specific, regional, and sectoral contributions of daily emissions for 3 air pollutants: fine particulate matter (PM2.5), ozone (O3), nitrogen dioxide (NO2). This is implemented Washington, DC, first 2011, identify urban pollution sources, again 2016, exa...

1998
Grigory V. Osipov James J. Collins

Here we propose mechanisms for controlling the movement and suppression of spiral waves in discrete excitable media. We show that the controlled drift and subsequent annihilation of a spiral wave can be achieved through the combination of two factors: the introduction of small spatial inhomogeneities in the medium and the interaction of the wave with the boundaries of the medium. The inhomogene...

Journal: :Molecules 2010
Werner Kaminsky Donald Responte Dan Daranciang Jose B Gallegos Bao-Chau Ngoc Tran Tram-Anh Pham

Three new enantiopure aryl-thioureas have been synthesized, N-(4-X-phenyl)-N-[1(S)-1-phenylethyl]thiourea, X= Cl, Br, and NO2 (compounds 1-3, respectively). Large single crystals of up to 0.5 cm(3) were grown from methanol/ethanol solutions. Molecular structures were derived from X-ray diffraction studies and the crystal morphology was compared to calculations employing the Bravais-Friedel, Don...

2016
Susan E. Tomlinson S. Veronica Tan David Burke Robyn W. Labrum Andrea Haworth Vaneesha S. Gibbons Mary G. Sweeney Robert C. Griggs Dimitri M. Kullmann Hugh Bostock Michael G. Hanna

Ion channel dysfunction causes a range of neurological disorders by altering transmembrane ion fluxes, neuronal or muscle excitability, and neurotransmitter release. Genetic neuronal channelopathies affecting peripheral axons provide a unique opportunity to examine the impact of dysfunction of a single channel subtype in detail in vivo. Episodic ataxia type 2 is caused by mutations in CACNA1A, ...

Journal: :Bulletin of the Chemical Society of Japan 1964

2008
Volker Teichgräber Martina Ulrich Nicole Endlich Joachim Riethmüller Barbara Wilker Anna M van Heeckeren Mark L Barr Gabriele von Kürthy Kurt W Schmid Michael Weller Burkhard Tümmler Florian Lang Heike Grassme Gerd Döring Erich Gulbins

Microbial lung infections are the major cause of morbidity and mortality in the hereditary metabolic disorder cystic fibrosis, yet the molecular mechanisms leading from the mutation of cystic fibrosis transmembrane conductance regulator (CFTR) to lung infection are still unclear. Here, we show that ceramide age-dependently accumulates in the respiratory tract of uninfected Cftr-deficient mice o...

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