- to compare colonization of group b streptococcus (gbs) in diabetic and non-diabetic pregnant women. in this prospective study 50 pregnant women with diabetes mellitus (both pregestational and gestational) and 43 pregnant women without diabetes between 33 and 37 weeks' gestation were evaluated. three samples for group b streptococcal culture detection were obtained from each subject in the fol...

background: previous studies have demonstrated that patients with insulin-dependent diabetes mellitus (iddm) have a high prevalence of osteopenia.  hypercalciuria has also been well documented in human diabetes and many children with insulin-dependent diabetes mellitus have short stature.   objective: to investigate the relationship of hypercalciuria and hyperphosphaturia with growth retardatio...

The degree of fasting hyperglycemia in patients with non-insulin-dependent diabetes mellitus is dependent on the rate of hepatic glucose production. The basal rate of hepatic glucose production is increased in patients with non-insulin-dependent diabetes mellitus, and there is a positive correlation between hepatic glucose production and fasting glucose levels. Diminished secretion of insulin, ...

Non-insulin-dependent diabetes mellitus (NIDDM) occurs predominantly after the age of 50 years but is not easy to distinguish from late onset insulin-dependent diabetes. It is likely that misclassification is rare in a Caucasian population. Whilst NIDDM is widely believed to be genetically determined, recent epidemiological observations have consistently revealed statistical associations betwee...

OBJECTIVE We studied the utility of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) for improving the accuracy of type 1 diabetes (T1D) risk classification in TrialNet Natural History Study (TNNHS) participants. RESEARCH DESIGN AND METHODS The cumulative incidence of T1D was compared between normoglycemic individuals with DPTRS values >7.00 and dysglycemic individuals in the TNNHS (n = ...

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Understanding the management of non-insulin-dependent (type 2) diabetes (NIDDM) requires the grasp of three concepts. Firstly, the condition is steadily progressive and demands appropriate changes of therapy over time. Secondly, therapeutic aims must be set for three parameters: plasma lipids, plasma glucose and blood pressure. Thirdly, the condition is dangerous and regular screening for early...

OBJECTIVE We assessed the accuracy of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS), developed from the Diabetes Prevention Trial-Type 1 (DPT-1), in the TrialNet Natural History Study (TNNHS). RESEARCH DESIGN AND METHODS Prediction accuracy of the DPTRS was assessed with receiver-operating characteristic curve areas. The type 1 diabetes cumulative incidence within the DPTRS interval...

Much of the public media discussion of genetics of common diseases has centered on opportunities for targeted preventive actions. At the same time, in the specialist literature, there has been extensive discussion of ‘‘interaction,’’ both between genes and between genes and environment. These two topics concern the use and interpretation of statistical models for risk of diseases with several, ...