نتایج جستجو برای: nonstructural protein 3

تعداد نتایج: 2817426  

Journal: :Journal of virology 2005
Rainer Gosert Wiebke Jendrsczok Jan Martin Berke Volker Brass Hubert E Blum Darius Moradpour

Protein-protein interactions involved in formation of the membrane-associated hepatitis C virus (HCV) replication complex are poorly understood. Here, we investigated nonstructural proteins with deletions in their membrane anchor domains when expressed in the context of the entire HCV polyprotein. Interactions among cytosolic domains of HCV nonstructural proteins were found not to be sufficient...

ژورنال: Vaccine Research 2017
El-Demella , MA, El-Rashidy , FH, Ghareeb, DA, Habashy , NH, Shaban , NZ,

Introduction: Dendritic cells (DCs) have been recently employed as carriers for vaccines against several viral infections. The present study was designed to develop a prophylactic vaccine against hepatitis C virus (HCV) using DCs treated with Berberis vulgaris root extract (BRE), as a preclinical study. Methods: BRE was prepared and injected to female BALB/c mice for DCs expansion. The expanded...

Journal: :Acta crystallographica. Section F, Structural biology and crystallization communications 2010
Yanlin Ma Cheng Chen Lei Wei Qingzhu Yang Ming Liao Xuemei Li

Avian infectious bronchitis virus (IBV), which causes respiratory disease in infected birds, belongs to coronavirus group 3. IBV encodes 15 nonstructural proteins (nsp2-nsp16) which play crucial roles in RNA transcription and genome replication. Nonstructural protein 9 (nsp9) has been identified as a protein that is essential to viral replication because of its single-stranded RNA-binding abili...

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