fifty-seven patients suffering from systemic lupus erythematosus with different clinical features were studied from various aspects of immunological abnormalities, including anti-nuclear antibodies; anti-dna; anti-sm (smith's antigen); and, other extractable nuclear antigens. the tests employed were microhemagglutination, counter immunoelecterphoresis, and radio immunoassay (ria). the compariso...

Genomic instability is a hallmark of malignant growth that frequently involves mitotic defects associated with centrosome abnormalities. However, the question of whether abnormal centrosomes cause genomic instability or develop secondary to other changes has not been conclusively resolved. Here we show that human papillomavirus (HPV)-16 E7 can induce abnormal centrosome synthesis before the dev...

Erythrocyte abnormality test has been used to detect the genotoxic effect of dyeing industry effluent on the fish. The 96h LC50 of effluent against Cirrhinus mrigala was calculated by Finney method and three sublethal concentrations 24.48%, 12.24% and 6.12% were made. Fishes were kept in concentrations and blood was smeared after 24h, 48h, 72h and 96h. Eleven types of erythrocyte abnormalities ...

Radiotherapy is frequently used as treatment for oral cancer either alone or in combination with surgery. Reaction of tumor tissue to radiotherapy often shows marked inter-individual variability making it difficult to assess and predict the treatment outcome for individual patients. Recently attention has been drawn towards the role of radiation induced nuclear changes to assess radiosensitivit...

BACKGROUND The present study aimed to evaluate the efficacy of the hyaluronic acid (HA) binding assay in the selection of motile spermatozoa with normal morphology at high magnification (8400x). METHODS A total of 16592 prepared spermatozoa were selected and classified into two groups: Group I, spermatozoa which presented their head attached to an HA substance (HA-bound sperm), and Group II, ...