The synthesis of membrane skeletal proteins in avian nucleated red cells has been the subject of extensive investigation, whereas little is known about skeletal protein synthesis in bone marrow erythroblasts and peripheral blood reticulocytes in mammals. To address this question, we have isolated nucleated red cell precursors and reticulocytes from spleens and from the peripheral blood, respect...

The cell in Image BCI-01 is a nucleated red blood cell (RBC). Although nucleated RBCs do not normally appear in the peripheral blood of an adult, it is not unexpected in this patient’s condition owing to hematopoietic bone marrow stress. Nucleated RBCs are immature erythrocytes that still retain their nucleus. The cell in this image is typical of those most often seen in the peripheral blood of...

The D antigen content of nucleated red cell precursors in human bone marrow was estimated using autoradiography and 125I-anti-D. D antigen first appeared in the pronormoblast, and the quantity of antigen progressively increased during red cell maturation. Maximal anti-D binding occurred on mature red blood cells. Pronormoblasts, basophilic normoblasts, polychromatophilic normoblasts, and orthoc...

BACKGROUND Little is known about risk factors associated with out-of-hospital outcomes in survivors of critical illness. We hypothesized that the presence of nucleated red blood cells in patients who survived critical care would be associated with adverse outcomes following hospital discharge. METHODS We performed a two-center observational cohort study of patients treated in medical and surg...

objective: elevated nucleated red blood cell (nrbc) count is introduced as a potential marker of intra-uterine growth restriction (iugr). to investigate the probable association regardless of any known underlying disease, we aimed to study disturbances in nrbc count in infants experiencing idiopathic iugr. materials and methods: twenty three infants regarded iugr without any known cause were ch...

background: blood is permanently exposed to oxidation stress and therefore has a high antioxidants capacity. many different factors increasing the demand for the antioxidant capacity can be observed in the stored blood of donors. consequently, damage to erythrocytes by free radicals may occur. so it is useful to control the alternation of anti-oxidant enzymes in stored blood at different days o...