نتایج جستجو برای: nucleobindin

تعداد نتایج: 97  

Journal: :The Journal of biological chemistry 2009
Bent Honoré

Tsukumo and colleagues (1) have recently reported that a proline residue at position 2 from the signal peptide cleavage site determines the export of nucleobindin 1 from the endoplasmic reticulum (ER) and subsequent transport to the Golgi. They also studied the localization of three CREC proteins, reticulocalbin, calumenin, and Cab45 that contain a proline at position 2 from the N-terminal sign...

2006
ARLINDO A. MOURA DAVID A. CHAPMAN GARY J. KILLIAN

We previously reported that accessory sex gland fluid (AGF) from high fertility (HF) bulls influenced the oocyte-penetrating capacity of cauda epididymal sperm from low fertility (LF) bulls, based on in vitro fertilization (IVF) assays. The present study determined if AGF proteins were associated with these effects. Nineteen IVF assays with 12 bulls were grouped as follows. Group I (n1⁄48): ass...

2017
Chunyu Wang Yulun Wang Wenchao Hu

BACKGROUND Nesfatin-1, originating from its precursor protein called nucleobindin 2 (NUCB2), plays an important role in glucose metabolism and diabetes. The aim of this study is to examine the association of the c.1012C>G (rs757081) polymorphism of NUCB2 gene with the presence of T2DM. METHODS This study was performed in a population of 396 patients with T2DM and 196 healthy subjects. The c.1...

Journal: :Cell 2015
Micah J. Niphakis Kenneth M. Lum Armand B. Cognetta Bruno E. Correia Taka-Aki Ichu Jose Olucha Steven J. Brown Soumajit Kundu Fabiana Piscitelli Hugh Rosen Benjamin F. Cravatt

Lipids play central roles in physiology and disease, where their structural, metabolic, and signaling functions often arise from interactions with proteins. Here, we describe a set of lipid-based chemical proteomic probes and their global interaction map in mammalian cells. These interactions involve hundreds of proteins from diverse functional classes and frequently occur at sites of drug acti...

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