نتایج جستجو برای: nucleotide polymorphism
تعداد نتایج: 201089 فیلتر نتایج به سال:
objective(s):organic anion transporter polypeptide 1b1 (oatp1b1) encoded by solute carrier organic transporter 1b1 (slco1b1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. aim of this study was to investigate the frequencies of functionally significant snps (388a>g and 521t>c) and their haplotypes in 6 ethnic groups of ...
conclusions rs1595065 could be recommended as a risk factor in regulating her4 expression and affecting her2 positivity incidence among bc patients. methods overall, 156 patients and controls were genotyped using rflp-pcr. armitage test for trend was utilized to investigate the association between rs1595065 and susceptibility to bc. the possible change in the interaction between rs1595065 and m...
in the present research, molecular detection of bovine leukocyte adhesion deficiency (blad) and complex vertebral malformation (cvm)in a population of iranian holstein cows has been carried outusing milk somatic cells by polymerase chain reaction-restriction fragment length polymorphism(pcr-rflp). the blad and cvm are monogenic and autosomal recessive heredity lethal syndrome in holstein-friesi...
objective: to investigate the association of c631t single nucleotide polymorphisms in spo11 gene with male infertilityfollowed by an in silico approach. spo11 is a gene involved in meiosis and spermatogenesis process, which in humans, this gene is located on chromosome 20 (20q13.2-13.3) with 13 exons. materials and methods: in a case-control study, 200 blood samples were collected from the ivf ...
background genome-wide association studies have shown that rs738491, rs2143571, and rs3761472 in the sorting and assembly machinery component 50 homolog (samm50) gene are significantly associated with susceptibility to nonalcoholic fatty liver disease (nafld). conclusions we first demonstrated that the rs738491 t allele, rs2143571 a allele, and rs3761472 g allele in the samm50 gene created susc...
objectives the aim of this study was to explore the association between axin2 gene polymorphism and papillary thyroid carcinoma (ptc). patients and methods 106 blood samples (56 ptc patients and 50 healthy controls) were drawn from china-japan :union: hospital in jilin province, china, during october 2010 to march 2011. a case-control study was designed to examine the association between axin2 ...
results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...
background: cytokines and specially interferon-gamma (ifn-g) are largely responsible for the regulation of the protective immune response against mycobacterial infections. several studies have clarified the importance of common variants of ifn- g gene regarding the susceptibility to tuberculosis. bacille calmette-guérin (bcg) vaccine that is used to prevent severe forms of tuberculosis could ...
Purpose: Estrogen as a crucial hormone during pregnancy acts by two types of receptors. Estrogen receptor alpha, expressed by estrogen receptor 1 (ESR1) gene, is more abundant and exists in all human reproductive systems. Association of ESR1 gene polymorphism has been shown in some reproductive fields such as spontaneous abortion, endometriosis-related infertility and in vitro fertili...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید