Two categories of reference limits can be discerned in biological monitoring: The first category identifies individuals who have been exposed to a toxic agent at work, and is based on the distribution of the concentration of the agent or its metabolite in the population that has not been exposed to the agent at work. The second category, for which the term biological action level (BAL) is propo...

Smaller is not always better: nanotechnology yields nanotoxicology Howard M. Kipen1 and Debra L. Laskin2 1Clinical Research and Occupational Medicine Division, Department of Environmental & Occupational Medicine, and Environmental & Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School; and 2Department of Pharmacology and T...

*Toxicology and Molecular Biology Branch, ‡Pathology and Physiology Research Branch, and §Biostatistics Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505; †Ankara University School of Pharmacy, Department of Toxicology, 06100 Ankara, Turkey; and \BRT-Burleson Research Technologies, Inc., 5706 ...

Advocates of the Precautionary Principle have recently called for a "new science" to support the goals of precaution-based environmental and occupational health policy. While much attention has been given to epidemiology, the evidentiary science most relevant to precaution, or prevention, is toxicology. Opportunities for enhancing the role of toxicology in public policy must consider current bi...

Steve Kleeberger and Matt Longnecker step up to serve with me as interim deputy editors in the absence of a full-time permanent editor. Steve and Matt have given generously of their time, expertise, and energy in helping to maintain EHP ’s scientific quality during a time of transition. Given EHP ’s broad scope of coverage, however, we felt the need to likewise broaden the scope of our science ...

A series of meetings concerning metal toxicology have been organized by the Scientific Committee on the Toxicology of Metals under the Permanent Commission and International Association on Occupational Health. Accumulation of toxic metals with special reference to their absorption, excretion, and biological half-times was discussed in Slanchev Bryag, Bulgaria, 1971, and in Buenos Aires, 1972. D...

State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China Department of Molecular & Genetic Toxicology, the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China Department of Occupational Medicine and Environmental Health, Jiangsu Key Laboratory of Cancer Biomark...