The stem and leaves of Gasteria bicolor afforded three new dihydroanthracenones namely 3,4-dihydro-2,6,9-trihydroxy-8-methyl-1(2H)-anthracenone (gasteriacenone A), 3,4-dihydro-2,4,9-trihydroxy-6-methoxy-8-methyl-1(2H)-anthracenone (gasteriacenone B) and 3,4-dihydro-4,6,9-trihydroxy-7-carbomethoxy-8-methyl-1(2H)-anthraceno ne (gasteriacenone C). Their structures were determined by spectroscopic ...

The title compound has been synthesized starting from 2-methoxybenzdiethylarnide (1).

The objectives of this research was to determine the chemical composition of roscoe extract from methanol and evaluation of antibacterial activity. The phytochemical compound screened by GC-MS method. Forty eight bioactive phytochemical compounds were identified in the methanolic extract of Zingiber officinale. The identification of phytochemical compounds is based on the peak area, retention t...

In this investigation the reaction of cyclohexanone 1 with benzaldehyde 2 yielded (E)-2benzylidenecyclohexanone 3, which on reaction with 3-oxo-N-phenylbutanamide afforded 1-(1, 4, 5, 6, 7, 8-hexahydro-2-hydroxy-1, 4-diphenylquinolin-3-yl) ethanone.4. While the treatment of 4 with ethylbromoacetate and bromophenylethanone afforded the compounds 5 and 6 respectively. However, treatment of 4 with...

A new bio-based dimethacrylate (EMHO) consisting of three isomers, that is (ethane-1,2-diyl-bis(9-methacryloyloxy-10-hydroxy octadecanoate) [EMHO-i1], ethane-1,2-diyl-9-hydroxy-10-methacryloyloxy-9′-methacryloyloxy-10′-hydroxy octadecanoate [EMHO-i2], and ethane-1,2-diyl-bis(9-hydroxy-10-methacryloyloxy [EMHO-i3]), was made by a three-step reaction starting from esterification oleic acid with e...

The synthesis and cytotoxic evaluation of 9-acyloxy 1,8-dichloroanthracene derivatives are described. The system selectively reduces the carbonyl group flanked by the peri substituents of the anthracenediones to give the corresponding 1,8-dichloro-9(10H)-anthracenone. Simple acylation of anthracenone occurred with appropriate acyl chlorides in CH2Cl2 with a catalytic amount of pyridine to give ...

Four new compounds, including a sesquiterpene and three aromatic compounds, and a known compound were isolated from a culture broth of the fungus Stereum sp. The novel sesquiterpene was determined to be stereumone A ((+)-2,3,4a,5,6,7,8a,9-octahydro-5-hydroxy-6,6,9-trimethyl-4,8a-epoxynaphtho[2,3-b]furan-8(8H)-one; 1), and the three new aromatic compounds were elucidated as 3,5-dihydroxy-4-(3-me...

Linopirdine (3,3-bis(4-pyridinylmethyl)-1-phenylindolin-2-one, DUP996) is an extensively studied representative of a class of cognition enhancing compounds that increase the evoked release of neurotransmitters. Recent studies suggest that these agents act through the blockade of specific K+ channels. We have recently identified more potent anthracenone analogs of linopirdine: 10,10-bis(4-pyridi...