Journal:
:avicenna journal of medical biochemistry
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fatemeh zeraati department of pharmacology, hamadan university of medical sciences, hamadan, ir iran; department of pharmacology, hamadan university of medical sciences, hamadan, ir iran.tel: +98-9183122063, fax: +98-8118226035
malihe araghchian department of pharmacology, hamadan university of medical sciences, hamadan, ir iran
farzaneh esna-ashari departmentof community medicine, hamadan university of medical sciences, hamadan ir iran
mohammad mehdi fazlian medical school hamadan university of medical sciences, hamedan ir iran
sima torabian medical school hamadan university of medical sciences, hamedan ir iran
nazanin fallah medical school hamadan university of medical sciences, hamedan ir iran
background ascorbic acid is amongst important water-soluble vitamins and when used orally in high-doses it has been observed to relieve pain and reduce opioid use in patients. however no controlled trial has compared the antinociceptive effects of ascorbic acid with other analgesic groups on animal models, and investigated the involved mechanisms. objectives in the present study, the antinocice...